胃癌患者腹腔镜切除术后发生胰瘘的危险因素分析  

Analysis on Risk Factors for Pancreatic Fistula after Laparoscopic Resection in Patients with Gastric Cancer

作　　者：康梦锴[1] 洛山[1] KANG Menghai;LUO Shan(Department of Gastroenterology and Proctology,Zhengzhou Third People's Hospital,Zhengzhou 450000,China)

机构地区：[1]郑州市第三人民医院胃肠肛肠科,河南郑州450000

出　　处：《临床医学工程》2024年第11期1427-1428,共2页Clinical Medicine & Engineering

摘　　要：目的分析胃癌患者腹腔镜切除术后发生胰瘘的危险因素。方法选取2018年3月至2023年10月在我院行腹腔镜切除术治疗的100例胃癌患者,统计其胰瘘发生情况,并收集其基线资料,进一步经单因素分析与多因素分析明确胰瘘发生的相关危险因素。结果100例胃癌患者腹腔镜切除术后胰瘘发生率为24.00%(24/100)。胰瘘组BMI>24 kg/m^(2)、手术时间≥4 h、接受新辅助化疗占比高于非胰瘘组(P<0.05)。多因素Logistic回归分析结果显示,BMI>24 kg/m^(2)、手术时间≥4 h、接受新辅助化疗是胃癌患者腹腔镜切除术后发生胰瘘的独立危险因素(OR>1,P<0.05)。结论胃癌患者腹腔镜切除术后胰瘘发生风险较高,胰瘘的发生受患者BMI、手术时间、是否接受新辅助化疗等因素影响,临床需对上述影响因素重点关注。Objective To analyze the risk factors for pancreatic fistula after laparoscopic resection in patients with gastric cancer.Methods 100 patients with gastric cancer undergoing laparoscopic resection in our hospital from March 2018 to October 2023 were selected,the incidence of pancreatic fistula was counted,and the baseline data were collected.The related risk factors for pancreatic fistula were further identified by univariate analysis and multivariate analysis.Results The incidence of pancreatic fistula after laparoscopic resection in 100 patients with gastric cancer was 24.00%(24/100).The proportion of patients with BMI>24 kg/m^(2),operation time≥4 h,and neoadjuvant chemotherapy in the pancreatic fistula group was higher than that in the non-pancreatic fistula group(P<0.05).Multivariate Logistic regression analysis showed that BMI>24 kg/m’,operation time≥4 h and neoadjuvant chemotherapy were independent risk factors for pancreatic fistula after laparoscopic resection in patients with gastric cancer(OR>1,P<0.05).Conclusions Patients with gastric cancer have higher risk of pancreatic fistula after laparoscopic resection.The occurrence of pancreatic fistula is affected by factors such as BMI,operation time and neoadjuvant chemotherapy,the above influencing factors need to be focused on in clinical practice.

关 键 词：胃癌 腹腔镜切除术 胰瘘 危险因素 

分 类 号：R735.2[医药卫生—肿瘤]