Mind-body control:a new perspective on motor neuron function  

作　　者：Maria-Luise Petrovic-Erfurth Albena Jordanova 

机构地区：[1]Molecular Neurogenomics Group,VIB Center for Molecular Neurology,VIB,2610 Antwerp,Belgium [2]Molecular Neurogenomics Group,Department of Biomedical Sciences,University of Antwerp,2610 Antwerp,Belgium [3]Molecular Medicine Center,Department of Medical Chemistry and Biochemistry,Medical University-Sofia,1431 Sofia,Bulgaria

出　　处：《Signal Transduction and Targeted Therapy》2024年第9期3557-3559,共3页信号转导与靶向治疗（英文）

基　　金：supported in part by the Fund for Scientific Research-Flanders(FWO)(research grants G048220N and G0A2122N to A.J.,postdoctoral fellowship,and KAN grant to M.-L.P.-E.);the French Muscular Dystrophy Association(AFM-Téléthon Trampoline Grant#21869 to M.-L.P.-E.and Research Grant#23708 to A.J.);the US National Institutes of Health(R21 NS120123-01A1,subaward#5-54586 to A.J.);the Belgian Association against Muscular Diseases(ABMM Grants to M.-L.P.-E.and A.J.);the Bulgarian National Recovery and Resilience Plan,financed by the National Science Fund of Bulgaria(BNSF)(#BG-RRP-2.004-0004-C01 to A.J.)。

摘　　要：A recent study published in Nature1 used an optogeneticallyactivated behavioral paradigm in fruit flies to demonstrate that individual motor neurons command their target muscles in a biased manner to execute body movements,based on the mechanosensory feedback preceding the movement.This finding contradicts the current postulate that activation of a specific motor neuron would always result in a pre-determined fixed muscle response,adding important new perspectives in the fields of neurobiology,biomechanics,and robotics.When a dancing ballerina executes her turns,she typically controls her head position and fixes her gaze on a single orientation point.This spotting technique helps her to maintain balance and to prevent dizziness during her complex movements.But how is this mind-body control achieved from a neurobiological point of view?

关 键 词：execute INDIVIDUAL MAINTAIN 

分 类 号：R745[医药卫生—神经病学与精神病学]