肝脏未分化胚胎性肉瘤的诊断及治疗  

Diagnosis and treatment of undifferentiated embryonal sarcoma of the liver

作　　者：李振[1] 刘婧[2] 王云慧[1] 孔文青 陈新国 赖建君 李启龙 马邦振 Li Zhen;Liu Jing;Wang Yunhui;Kong Wenqing;Chen Xinguo;Lai Jianjun;Li Qilong;Ma Bangzhen(Department of Pediatric Surgery,Yantai Yuhuangding Hospital,Qingdao University,Yantai 264000,China;Department of Pathology,Yuhuangding Hospital,Qingdao University,Yantai 264000,China;Operation Room of Yantai Yuhuangding Hospital,Qingdao University,Yantai 264000,China;Department of Pediatric Surgery,Provincial Hospital of Shandong First Medical University,Ji'nan 250000,China;Department of Surgery,Provincial Hospital,Shandong First Medical University,Ji'nan 250000,China;Department of Statistics and Medical Records Management,Provincial Hospital,Shandong First Medical University,Ji'nan 250000,China)

机构地区：[1]青岛大学附属烟台毓璜顶医院普外儿外科,烟台264000 [2]青岛大学附属烟台毓璜顶医院病理科,烟台264000 [3]青岛大学附属烟台毓璜顶医院中区手术室,烟台264000 [4]山东第一医科大学附属省立医院儿外科,济南250000 [5]山东第一医科大学附属省立医院外科门诊,济南250000 [6]山东第一医科大学附属省立医院统计与病案管理科,济南250000

出　　处：《中华普通外科杂志》2024年第10期797-800,共4页Chinese Journal of General Surgery

基　　金：山东第一医科大学(山东省医学科学院)青年科学基金培育资助计划(202201-051)。

摘　　要：目的总结肝脏未分化胚胎性肉瘤的临床病理特点。方法回顾性分析山东省立医院及烟台毓璜顶医院综合性医学中心2000年1月至2023年1月收治的16例肝脏未分化胚胎性肉瘤患者的临床资料。结果16例患者均经病理明确证实。症状以腹部包块、腹痛不适为主,实验室检查无特异性肿瘤学指标,影像检查多以囊实性成分为主。14例行根治性手术切除,术后最短生存时间7个月,最长时间121个月,中位生存时间35.9个月。结论肝脏未分化胚胎性肉瘤是一种极其罕见的肝脏恶性肿瘤,临床表现不典型,CT检查有助于诊断。确诊需病理检查。该病患者预后较差,手术切除是有效的治疗手段。Objective To summarize the clinicopathologic characteristics of undifferentiated embryonal sarcoma of the liver.Methods The clinical data of 16 patients with undifferentiated embryonal sarcoma of the liver admitted to Shandong Provincial Hospital and Yantai Yuhuangding Hospital from Jan 2000 to Jan 2023 was retrospectively analyzed.Results The diagnosis of undifferentiated embryonal sarcoma in all the 16 patients was established by postoperative pathology.The clinical manifestations of the patients were mainly asymptomatic abdominal mass,abdominal pain and discomfort.The laboratory examination was mostly nonspecific,the image exam showed mostly solid cystic mass.14 cases underwent radical surgical resection.The minimum survival time was 7 months,maximum survival time was 121 months with median survival time of 35.9 months.Conclusions Undifferentiated embryonal sarcoma of the liver is an extremely rare malignant tumor of the liver.The disease lacks specific clinical manifestations.CT examination can assist in the diagnosis of the disease.Diagnosis of undifferentiated embryonal sarcoma of the liver depends on pathological examination.The prognosis of patients is poor,surgical resection of the tumor is an effective treatment.

关 键 词：肝肿瘤 肉瘤 诊断 治疗 

分 类 号：R735.7[医药卫生—肿瘤]