抑郁个体对奖赏反馈的加工及其神经机制研究  

Research of reward feedback processing and its neural mechanism in depressed individuals

作　　者：李雨桐 林嘉琪 Li Yutong;Lin Jiaqi(College of Psychology,Liaoning Normal University,Dalian 116029,China)

机构地区：[1]辽宁师范大学心理学院,辽宁大连116029

出　　处：《辽宁师范大学学报（社会科学版）》2024年第6期61-68,共8页Journal of Liaoning Normal University(Social Science Edition)

基　　金：国家社会科学基金一般项目“抑郁倾向个体言语情绪信息加工偏向及阅读干预”(BBA230066);教育部产学合作协同育人项目“抑郁倾向个体言语情绪信息加工偏向”(230907276300605)。

摘　　要：快感缺失症状改善是抑郁个体在临床上病情康复或缓解的重要指标,这引起了研究者对抑郁个体的奖赏反馈加工及其神经机制的广泛关注。对抑郁个体的奖赏反馈加工及其神经机制进行梳理和总结发现,抑郁个体比健康个体对奖赏反馈的敏感性低,这可能与抑郁个体获得奖励的动机不足、对情绪情境不敏感、感知控制能力降低等有关。对抑郁个体的奖赏反馈所产生的RewP、fb-P3以及LPP成分结果进行分析,认为神经机制不一致性可能与任务范式以及考察群体之间的差异有关。未来研究可细化奖赏类型,探究抑郁个体对不同反馈物加工的神经基础;采用脑成像技术定位奖赏反馈加工脑区,以支持现有电生理研究的结论;推广研究至抑郁倾向个体。The improvement of anhedonia symptoms is an important index for the recovery or remission of depressed individuals,which has attracted attention of researchers on the reward feedback processing and its neural mechanism in depressed individuals.The processing and neural mechanism of reward feedback in depressed individuals were summarized in this paper.The results showed that depressed individuals were less sensitive to reward feedback than healthy individuals,which may be related to the lack of motivation to get rewards,insensitivity to emotional situations and reduced perceptual control.The results of the RewP,fb-P3 and LPP components produced by the reward feedback of depressed individuals were analyzed,indicating that the neural mechanism inconsistency may be related to the task paradigm and the differences among examined groups.Future studies can refine reward types and explore the neural basis of processing different feedback in depressed individuals.Brain imaging technology was used to locate the reward feedback processing brain region to support conclusions of existing electrophysiological studies and extend the study to individuals prone to depression.

关 键 词：抑郁症 奖赏反馈加工 RewP fb-P3 LPP 

分 类 号：B842.6[哲学宗教—基础心理学]