多发性硬化发病机制和中西医治疗研究进展  

Research progress on the pathogenesis of multiple sclerosis and the treatment of traditional Chinese and Western medicine

作　　者：徐佳琴 熊英琼 XU Jiaqin;XIONG Yingqiong(Jiangxi University of Chinese Medicine,Nanchang 330004,China;The First Affiliated Hospital of Nanchang University,Nanchang 330006,China)

机构地区：[1]江西中医药大学,江西南昌330004 [2]南昌大学第一附属医院,江西南昌330006

出　　处：《中国实用神经疾病杂志》2024年第11期1439-1443,共5页Chinese Journal of Practical Nervous Diseases

基　　金：国家自然科学基金资助项目(编号:82160245)。

摘　　要：多发性硬化(MS)是一种罕见的自身免疫性疾病,具有高致残性特点,好发于青壮年,发病率逐年递增,临床治疗效果一般,预后不良,严重影响患者生活质量。近年来国内外学者对其研究颇多,针对发病机制的深入研究发现了许多治疗新靶点,相关治疗药物也不断更新,对多发性硬化证的治疗和预后有极大作用。基于此,本研究对近5 a来多发性硬化的机制研究与中西医治疗进展作一综述,希望给多发性硬化的临床治疗及科研工作提供新思路。Multiple sclerosis(MS)is a rare autoimmune disease with high disabling characteristics,more likely to occur in young adults,the incidence is increasing year by year,clinically its treatment effect is average,the prognosis is poor,and the quality of life of patients is seriously reduced.In recent years,scholars at home and abroad have made a lot of progress in his research,and many new therapeutic targets have been discovered in in-depth research on pathogenesis,and related therapeutic drugs have been continuously updated,which has a great effect on the treatment and prognosis of multiple sclerosis.Based on this,the author reviews the mechanism research of multiple sclerosis and the progress of traditional Chinese and Western medicine treatment in the past five years,hoping to provide new ideas for the clinical treatment and scientific research of multiple sclerosis.

关 键 词：多发性硬化 发病机制 实验性自身免疫性脑脊髓炎 免疫性疾病 中西医治疗 

分 类 号：R744.51[医药卫生—神经病学与精神病学]