能谱CT双低对比剂扫描联合多模型迭代重建在CT门静脉成像中的应用  

Application of energy spectrum CT dual low contrast scanning combined with multi model iterative reconstruction in CT portal vein

作　　者：孙天友 胡春峰 SUN Tianyou;HU Chunfeng(Department of Imaging,Affiliated Hospital of Xuzhou Medical University,Xuzhou 221006,China;First Affiliated Hospital of Bengbu Medical University,Bengbu 233000,China)

机构地区：[1]徐州医科大学附属医院影像科,江苏徐州221006 [2]蚌埠医科大学第一附属医院,安徽蚌埠233000

出　　处：《分子影像学杂志》2024年第11期1243-1248,共6页Journal of Molecular Imaging

摘　　要：目的探讨能谱CT低用量、低浓度对比剂联合不同权重ASIR-V技术在门静脉成像中的应用效果。方法前瞻性收集2023年11月~2024年4月在蚌埠医科大学第一附属医院做门静脉CT检查的84例患者,随机分为A、B两组,42例/组。A组行能谱CT联合前置60%ASIR-V扫描,碘佛醇320 mgI/mL,用量按1.2 mL/kg计算,按10 keV的间隔提取40~80 keV的单能量图像,再间隔20%的权重重建后置ASIR-V 20%~80%重组,得到20个亚组的门静脉图像;B组行常规CT联合前置0%ASiR-Vs扫描,碘佛醇350 mgI/mL,用量按1.5 mL/kg计算,自动输出120 kV、前后置0%ASIR-V的图像。分别测量计算两组图像门静脉主干最大层面及同层面肝脏实质和竖脊肌的CT值、噪声(SD)、信噪比(SNR)和对比噪声比(CNR),综合评价出A组中得分最高的亚组命名为A1组。结果固定单能量能级时,增加后置ASIR-V的权重,图像噪声降低(P<0.001),SNR和CNR增加。A组图像中,60 keV联合前置60%ASIR-V,后置60%ASIR-V的图像评分最高,其背景SD为26.06±3.95 HU,高于对照组18.80±2.39 HU(P<0.001);A组SNR、CNR均高于B组(P<0.001),碘摄入量、有效辐射剂量低于B组(P<0.001)。A1组图像主观评分略低于B组,差异不具有统计学意义。结论在门静脉能谱CT成像中,应用低用量、低浓度对比剂联合前、后置ASIR-V技术可以明显降低辐射剂量和碘摄入量。Objective To explore the application effect of low dosage and low concentration of contrast agent combined with different weights of ASIR-V in portal vein spectroscopy CT examination.Methods We collected 84 patients who underwent portal vein CT enhancement examination at the First Affiliated Hospital of Bengbu Medical University from November 2023 to April 2024 and then randomly divided into A and B group,with 42 cases in each.In group A,the patients underwent energy spectrum CT combined with 60%adaptive statistical iterative reconstruction-V(ASIR-V)scanning.The iodine contrast concentration used was 320 mgI/mL,and the contrast agent dosage was calculated as 1.2 mL/kg.Additionally,single energy images ranging from 40 to 80 keV were extracted from the original data at 10 keV intervals.The portal vein images of 20 subgroups were reconstructed using ASIR-V with increments of 20%(ranging from 20%-80%).Group B underwent a CT scan with conventional CT combined with a 0%ASIR-V preposition,iodine contrast concentration of 350 mgI/mL,and a contrast agent dosage calculated at 1.5 mL/kg.Images with 120 kV were automatically output with a 0%ASIR-V preposition.The CT values,noise(SD),signal-to-noise ratio(SNR),and contrast-to-noise ratio(CNR)of the largest portal vein main layer,as well as the liver parenchyma and erector spinal muscle of the same layer,were measured and calculated in both groups.Subsequently,the imaging diagnostic physician conducted a subjective assessment of the image quality.Objective image quality indicators and the amount of contrast agent were analyzed using independent sample t-test and Kruskal-Wallis H test,while subjective image indicators were assessed using the Kappa consistency test.Results The increase in post-ASIR-V weight resulted in a significant decrease in image noise(P<0.001)and an increase in both SNR and CNR.In group A,the background SD of 60keV,with 60%ASIR-V preposition and 60%ASIR-V postposition,was 26.06±3.95 HU,significantly higher than that of the control group(18.80±2.39 HU)(P<0

关 键 词：能谱CT 门静脉 ASIR-V权重水平 辐射剂量 对比剂 

分 类 号：R735.7[医药卫生—肿瘤] R730.44[医药卫生—临床医学]