High-intensity focused ultrasound strategies for treating prostate cancer  

作　　者：Xiaobo Wu Yupeng Wu Chi-Fai Ng Chi-Hang Yee Peter Ka-Fung Chiu 

机构地区：[1]SH Ho Urology Centre,Department of Surgery,Faculty of Medicine,The Chinese University of Hong Kong,Hong Kong,China [2]Department of Urology,The First Affiliated Hospital of Fujian Medical University,Fuzhou 350004,China

出　　处：《Asian Journal of Andrology》2024年第6期595-599,共5页亚洲男性学杂志（英文版）

摘　　要：Prostate cancer (PCa) is a significant health concern globally, necessitating effective treatment options. Typical treatment methods for early stage, particularly localized PCa, encompass radical procedures, such as radical prostatectomy (RP) and radiotherapy (RT), and nonradical focal therapy (FT). FT is a focused approach mainly used for treating small lesions limited to a specific zone of the prostate. Its objective is to achieve cancer control when minimizing damage to benign tissue. High-intensity focused ultrasound (HIFU) is one of the most used modalities in FT for the management of PCa. The progress in HIFU technology showcases continuous advancements, offering clinicians a variety of strategies to cater to diverse patient requirements. The advancements include the development of transrectal and transurethral HIFU machines that offer enhanced treatment distances, magnetic resonance imaging (MRI) fusion capabilities, real-time monitoring, and precise ablation. These improvements contribute to increased treatment effectiveness and better outcomes for patients. This narrative review aims to summarize the use of HIFU technology and its evolution, offering diverse options to clinicians, and explores the safety, effectiveness, and quality of different HIFU strategies, such as whole-gland ablation, hemigland ablation, and focal ablation. We conclude that nonwhole-gland HIFU offers similar cancer control with better short-term functional outcomes and fewer complications compared to whole-gland ablation. Combining HIFU with transurethral resection of the prostate (TURP) improves urinary function and reduces catheterization time. Focal ablation and hemigland ablation show promise in achieving cancer control when preserving continence and potency.

关 键 词：ablation focal therapy high-intensity focused ultrasound prostate cancer STRATEGY 

分 类 号：R737.25[医药卫生—肿瘤]