实地导航训练提高大脑功能连接模式稳定性  

Real-world navigation training enhances the stability of large-scale brain connectivity patterns

作　　者：俞梦霞 宋宜颖 刘嘉[3] YU Mengxia;SONG Yiying;LIU Jia(Bilingual Cognition and Development Lab/Center for Linguistics and Applied Linguistics,Guangdong University of Foreign Studies,Guangzhou 510420,China;Faculty of Psychology,Beijing Normal University,Beijing 100875,China;Department of Psychological and Cognitive Sciences,Tsinghua University,Beijing 100084,China)

机构地区：[1]广东外语外贸大学外国语言学及应用语言学研究中心/双语认知与发展实验室,广州510420 [2]北京师范大学心理学部,北京100875 [3]清华大学心理与认知科学系,北京100084

出　　处：《心理学报》2024年第12期1661-1675,共15页Acta Psychologica Sinica

基　　金：国家自然科学基金(32200879);广州市基础与应用基础研究项目(SL2022A04J00071)资助

摘　　要：空间导航主要依赖于两种空间表征:自我中心参照表征与环境中心参照表征。然而,个体在现实环境中的空间导航能力提升与这两种空间表征存在何种关联仍未可知。为此,本研究结合行为测量与功能核磁共振技术(fMRI),对非熟悉环境实地空间导航训练前后个体空间导航能力和大脑全局性功能连接模式的改变进行分析,系统考察个体实地空间导航能力提高的内在神经机制。研究结果发现,训练组被试在训练后进行空间导航任务时,自我中心参照表征的核心脑区——顶上小叶(SPL)的神经活动显著增强。更为重要地,训练显著提高了以SPL为核心的全脑功能连接模式的稳定性,且与个体导航任务表现的提高呈正相关。上述结果表明,实地空间导航能力的提高与自我中心参照表征的增强存在密切关联,并进一步表现为SPL与全脑其他区域的信息交互通路的固化。Spatial navigation involves both egocentric(body-centered)and allocentric(environment-centered)spatial representations,which are hosted in structurally and functionally segregated brain regions.The two types of representations are flexibly weighted in response to changing environmental cues and landmarks during the navigational process,thereby achieving a stable and robust neural code of the target location.However,it remains unknown whether and how improvements in real-world navigational proficiency are related to these two types of spatial representations.In the present study,participants who were unfamiliar with the campus layout(newly arrived university freshmen)received a real-world navigation training for 20 days.Before and after the training,participants received fMRI scanning when they performed a distance judgment task and a paper folding task(as a control).In addition,they were comprehensively tested for their navigational ability via several behavioral tasks(live pointing,offsite direction estimation and offsite distance estimation)outside the scanner.A control group comprised participants who underwent the same fMRI scanning and behavioral tests but did not receive any training.By comparing the training-induced changes in regional activation and task-based global functional connectivity(FC)patterns between the two groups,we investigated the neural correlates of the improvement in real-world navigation performance.We found that the real-world navigation training improved participants'performance during all the behavioral tasks.At the neural level,we observed significant training-induced activation enhancement in the right superior parietal lobule(rSPL),a core brain region that hosts egocentric representation.Moreover,the training increased the global FC pattern stability with the rSPL as the seed region during the distance judgment task,although it had no significant effects on the FC pattern stability during the baseline task.Finally,the increase in global FC pattern stability also predicted individua

关 键 词：空间导航 自我中心参照 顶上小叶 功能连接模式 

分 类 号：B842[哲学宗教—基础心理学]