Visible-light induced photocatalyst-free difluoromethylation of quinoxalinones with difluorosulfones  

作　　者：Linlin Shi Tiantian Li Wenjing Zhang Weinan Hu Xinju Zhu Yixin Lu Guang-Jian Mei 

机构地区：[1]Green Catalysis Center,and College of Chemistry,Zhengzhou University,Zhengzhou,Henan 450001,China [2]Department of Chemistry,National University of Singapore,3 Science Drive 3,117543,Singapore

出　　处：《Green Synthesis and Catalysis》2024年第4期277-281,共5页绿色合成与催化（英文）

基　　金：Financial support from the National Natural Science Foundation of China(Nos.22101267,U1904212,U2004191 and 21803059)is gratefully appreciated.

摘　　要：Visible-light induced direct C–H difluoromethylation of quinoxalinones with 2-((difluoromethyl)sulfonyl)benzo[d]thiazole has been developed for the first time.A broad range of quinoxalinones were well tolerated and reacted with difluorosulfone smoothly to give the corresponding products in moderate to good yields.Notably,no external photocatalyst or oxidant was required,which provides a practical and green protocol to access difluoromethylated quinoxalinones.Finally,the control experiments demonstrated a radical mechanism,and the density functional theory(DFT)calculations indicated the radicals were generated through the formation of an electron donoracceptor(EDA)complex.

关 键 词：Quinoxalinones DIFLUOROMETHYLATION Visible-light induced Photocatalyst-free Difluorosulfones 

分 类 号：O62[理学—有机化学]