Controlled coupling and characterization of oyster (Crassostrea gigas) ferritin with gold nanostars  

作　　者：Han Li Xiaoyu Xia Shuzhen Cheng Jiachen Zang Zhenyu Wang Xianbing Xu Ming Du 

机构地区：[1]School of Food Science and Technology,National Engineering Research Center of Seafood,Collaborative Innovation Center of Seafood Deep Processing,Dalian Polytechnic University,Dalian 116034,China [2]College of Food Science and Nutritional Engineering,China Agricultural University,Beijing 100083,China

出　　处：《Food Science and Human Wellness》2024年第6期3202-3209,共8页食品科学与人类健康（英文）

基　　金：supported by the National Natural Science Foundation of China(31730069 and 31771926).

摘　　要：Ferritin has good thermal stability,resistance to certain acids and bases,and targeting,and has broad application prospects in the synthesis of gold nanostars(AuNS).In this study,we screened monodisperse AuNS with uniform particle size and morphology through a one-step synthesis method and coupled the synthesized AuNS with oyster ferritin(GF1).The results showed that the surface plasmon resonance(SPR)peaks of the coupled GF1@AuNS changed signifi cantly,and the changes in infrared spectra and potential confirmed the success of the synthesis,while the microscopic morphology showed an increase in particle size and surface peak coverage.Furthermore,GF1@AuNS does not induce cell death in the 100µmol/L range,is highly stable in physiological environments,and exhibits good X-ray attenuation in micro-computed tomography.Due to the unique functional activity of ferritin and AuNS,GF1@AuNS has potential applications in food detection and drug development in the future.

关 键 词：Gold nanostars(AuNS) Oyster ferritin Synthesis Structure Micro-computed tomography 

分 类 号：TS254.1[轻工技术与工程—水产品加工及贮藏工程]