Metagenomic next-generation sequencing identified a brain abscess caused by mixed oral anaerobe infection:A case report  

作　　者：Zepeng Ma Hui Liu Ming Liu Yuhao Wang Chao Li Yifei Xu 

机构地区：[1]Department of Microbiology,School of Public Health,Cheeloo College of Medicine,Shandong University,Jinan 250000,China [2]Jinan Center for Disease Control and Prevention,Jinan 250000,China [3]Suzhou Research Institute of Shandong University,Suzhou 215000,China

出　　处：《Infectious Medicine》2024年第2期107-112,共6页感染医学（英文）

基　　金：supported by the Taishan Scholars Project(tsqn202306003);the Shandong Excellent Young Scientists Fund Program(2022HWYQ-056);the Program of Science and Technology of Suzhou(2022SS15).

摘　　要：Fusobacterium vincentii brain abscesses are relatively rare.Here,we report our treatment of an anaerobic brain abscess caused by a mixed infection of Parvimonas micra,Streptococcus constellatus,Fusobacterium vincentii,and Bacteroides heparinolyticus diagnosed by metagenomic next-generation sequencing(mNGS).This is the first re-ported case of Fusobacterium vincentii in a brain abscess.This case highlights the possibility that oral anaerobic microbes can cause a brain abscess and demonstrates that mNGS has the potential to be deployed to provide rapid infection diagnosis and rationalize antimicrobial therapy for brain abscesses.

关 键 词：Anaerobic brain abscess Parvimonas micra Streptococcus constellatus Fusobacterium vincentii Bacteroides heparinolyticus mNGS 

分 类 号：R742.7[医药卫生—神经病学与精神病学]