宫颈癌腔内放疗患者疾病进展恐惧变化轨迹及影响因素分析  

Analysis of trajectory and influencing factors of fear of disease progression in patients with endovascular radiotherapy for cervical cancer

作　　者：张艳飞[1] 张位位 Zhang Yanfei;Zhang Weiwei(Department of Radiotherapy,Nanjing Chest Hospital,Nanjing Jiangsu 210029,P.R.China)

机构地区：[1]南京市胸科医院放疗科,江苏南京210029

出　　处：《中国计划生育和妇产科》2024年第11期84-89,共6页Chinese Journal of Family Planning & Gynecotokology

摘　　要：目的 探讨宫颈癌腔内放疗患者疾病进展恐惧变化轨迹及影响因素分析。方法 选择2020年5月至2021年3月在南京市胸科医院救治的181例宫颈癌腔内放疗患者,采用一般资料调查表、恐惧疾病进展简化量表(FoP-Q-SF)、家庭关怀度指数量表(PAGAR)以及自我感受负担量表进行基线调查,调查结束后于患者放疗前、放疗结束时、放疗结束1个月、放疗结束3个月(T0~T3)随访患者的疾病进展恐惧水平,分析不同时段的疾病进展恐惧水平差异,采用潜类别模型识别疾病进展恐惧变化轨迹亚组,最后采用决策树模型分析影响疾病进展恐惧变化轨迹亚组的因素。结果 宫颈癌腔内放疗患者不同随访时间点疾病进展恐惧得分依次为:T0(36.41±7.35)分、T1(37.83±9.16)分、T2(40.62±10.28)分、T3(42.41±10.35)分,不同时间点疾病进展恐惧得分差异有统计学意义(P<0.01);通过潜类别模型共识别出中疾病恐惧-快速上升组(17.68%)与低疾病恐惧-缓慢上升组(82.32%)2条疾病进展恐惧变化轨迹;通过决策树分析结果显示,年龄、受教育程度、宫颈癌分期、家庭月收入、家庭功能、自我感受负担均可预测宫颈癌腔内放疗患者的疾病进展恐惧变化轨迹,其中家庭功能是否良好为重要的影响因素。结论 宫颈癌腔内放疗患者疾病进展恐惧水平总体呈上升趋势,疾病进展恐惧变化轨迹存在一定群体异质性,家庭功能是其核心影响因素,医务人员可根据上述因素,早期识别中疾病恐惧-快速上升高危患者并及时制定以家庭功能为核心的干预方案,有助于降低患者疾病进展恐惧水平。Objective To investigate the trajectory of fear of disease progression and analysis of influencing factors in patients with endovascular radiotherapy for cervical cancer.Methods A total of 181 patients with endovascular radiotherapy for cervical cancer treated in Nanjing Chest Hospital from May 2020 to March 2021 were selected.Baseline investigation was conducted using the general data questionnaire,fear of progression questionnaire-short form(FoP-Q-SF),family PAGAR index(PAGAR)and self-perceived burden scale.After the investigation,patients were followed up before radiotherapy,at the end of radiotherapy,1 month after radiotherapy and 3 months after radiotherapy(T0~T3).Differences in the fear of progression of cervical cancer patients at different time periods were analyzed,and subgroups of fear of progression were identified by the latent category model.Finally,the decision tree model was used to analyze the factors affecting the trajectory of fear change in disease progression.Results The scores of the patients with intralucal radiotherapy for cervical cancer at different follow-up time points were 36.41±7.35 points in T0,37.83±9.16 points in T1,40.62±10.28 points in T2,42.41±10.35 points in T3,and there were significant differences in the scores at different time points(P<0.01).According to the latent category model,two fear trajectories of disease progression were identified in the medium disease fear-fast rising group(17.68%)and the low disease fear-slow rising group(82.32%).The results of decision tree analysis showed that age,education level,stage of cervical cancer,monthly family income,good family function and self-perceived burden could all predict the trajectory of fear of disease progression in patients with endovascular radiotherapy for cervical cancer,among which good family function was the most important influencing factor.Conclusion The level of fear of disease progression in patients with intracavitary radiotherapy for cervical cancer is generally on the rise,and there is a certain group het

关 键 词：宫颈癌腔内放疗 疾病进展恐惧 变化轨迹 影响因素 

分 类 号：R737.33[医药卫生—肿瘤]