血清铁蛋白在成年女性抑郁发作诊断中的应用价值  

The value of serum ferritin in the diagnosis of depressive episodes in adult women

作　　者：黄宇辉[1] 

机构地区：[1]中山大学附属第五医院检验科,广东珠海519000

出　　处：《医学前沿》2024年第13期5-6,共2页Frontiers of Medicine

摘　　要：目的:探讨血清铁蛋白在成年女性抑郁发作诊断中的应用价值。方法:研究对象为2022年1月至2024年5月在中山大学附属第五医院治疗的140例18-65岁抑郁发作女性患者和同期体检的180例健康女性。检测两组的外周血铁蛋白水平,并评估抑郁严重程度与铁蛋白水平的相关性。结果:抑郁发作患者的血清铁蛋白水平显著低于健康对照组(P<0.001),且铁蛋白水平与抑郁严重程度负相关。结论:血清铁蛋白可能作为诊断抑郁发作的生物标志物,监测铁蛋白水平对判断抑郁症的发生发展具有重要临床意义。Objective:To explore the application value of serum ferritin in diagnosing depressive episodes in adult women.Methods:The study included 140 women aged 18-65 with depressive episodes treated at the Fifth Affiliated Hospital of Sun Yat-sen University from January 2022 to May 2024,and 180 healthy women who underwent physical examinations at the same hospital during the same period.Serum ferritin levels were measured in both groups,and the correlation between depression severity and ferritin levels was assessed.Results:Serum ferritin levels were significantly lower in women with depressive episodes compared to healthy controls(P<0.001),and ferritin levels were negatively correlated with depression severity.Conclusion:Serum ferritin may serve as a potential biomarker for diagnosing depressive episodes.Monitoring ferritin levels is clinically significant for assessing the occurrence and development of depression.

关 键 词：抑郁发作 成年女性 血清铁蛋白 抑郁症 铁蛋白水平 健康女性 生物标志物 外周血 

分 类 号：R73[医药卫生—肿瘤]