甲状腺素在老年性黄斑变性中的作用研究进展  

Research progress on the role of thyroxine in age-related macular degeneration

作　　者：王松[1] 王杰[1] 张红兵 WANG Song;WANG Jie;ZHANG Hongbing(Department of Ophthalmology,First Affiliated Hospital of Northwest University,Shaanxi Ophthalmological Institute,Xi’an 710002,Shaanxi Province,China)

机构地区：[1]西北大学附属第一医院(西安市第一医院)眼科,陕西省眼科研究所,陕西省西安市710002

出　　处：《眼科新进展》2024年第12期1005-1008,共4页Recent Advances in Ophthalmology

基　　金：陕西省自然科学基础研究计划(编号:2021JZ-60)。

摘　　要：老年性黄斑变性(AMD)是一种以黄斑区脉络膜新生血管形成为特性的老年人常见的不可逆致盲性眼病。甲状腺素及其受体在视网膜中显著表达,游离的甲状腺激素与AMD的发生发展密切相关。本文总结了甲状腺素在AMD中的基础和临床研究进展,以期为进一步探索AMD的发病机制以及更好的防治该病提供科学理论依据。Age-related macular degeneration(AMD)is a common irreversible blinding eye disease in the elderly characterized by choroidal neovascularization in the macular area.Thyroxine and its receptors are significantly expressed in the retina,and free thyroid hormones are closely related to the occurrence and development of AMD.This article summarizes the basic and clinical research progress of thyroxine in AMD,in order to provide scientific theoretical basis for further exploring the pathogenesis of AMD and better prevention and treatment of the disease.

关 键 词：甲状腺素 老年性黄斑变性 受体 

分 类 号：R774.5[医药卫生—眼科]