Transition metal-free tunable synthesis of 3-(trifluoromethylthio)and 3-trifluoromethylsulfinyl chromones via domino C-H functionalization and chromone annulation of enaminones  

作　　者：Tao Zhou Jing Zhou Yunyun Liu Jie-Ping Wan Fen-Er Chen 

机构地区：[1]College of Chemistry and Chemical Engineering,Jiangxi Normal University,Nanchang 330022,China [2]Engineering Center of Catalysis and Synthesis for Chiral Molecules,Fudan University,Shanghai 200433,China

出　　处：《Chinese Chemical Letters》2024年第11期340-343,共4页中国化学快报（英文版）

基　　金：financially supported by National Natural Science Foundation of China(No.22161022)。

摘　　要：The new reactions between o-hydroxyphenyl enaminones and Langlois reagent(CF_(3)SO_(2)Na)for the tunable synthesis of 3-(trifluoromethylthio)chromones and 3-trifluoromethylsulfinyl chromones are reported herein.Both type of reactions proceed under transition metal-free conditions.In addition,the conditions for the synthesis of 3-trifluoromethylsulfinyl chromones have also been found to be applicable for the synthesis of 3-alkyl/arylsulfinyl chromones.

关 键 词：ENAMINONE C-H functinalizaiton Tunable synthesis Trifluoromethylthiolation Trifluoromethylsulfination Transition metal-free Sulfur functionalized chromones 

分 类 号：O621.25[理学—有机化学]