血流量变化和MR信号强弱与微波消融治疗子宫肌瘤疗效的关联性研究  

Study on correlation between changes in blood flow,MR signal intensity and the efficacy of microwave ablation for uterine fibroids

作　　者：罗常华[1] 李松珊 杨敬秋 吴映波[1] 莫鹏[1] 牟夏 陈超兰 高丽莉 LUO Changhua;LI Songshan;YANG Jingqiu;WU Yingbo;MO Peng;MOU Xia;CHEN Chaolan;GAO Lili(Department of Gynecology,Red Cross Hospital of Yulin City,Yulin 537000,Guangxi,China)

机构地区：[1]广西玉林市红十字会医院妇科,广西玉林537000

出　　处：《右江医学》2024年第10期894-899,共6页Chinese Youjiang Medical Journal

基　　金：广西壮族自治区卫生健康委员会自筹经费科研课题(Z20210837)。

摘　　要：目的探讨血流情况和磁共振(MR)信号强度与微波消融治疗子宫肌瘤疗效的关系。方法选择2021年7月至2023年6月广西玉林市红十字会医院经MR诊断的子宫肌瘤患者64例(共79个肌瘤),行微波消融术治疗。根据MR信号强度将其分为高信号组(n=19)、等信号组(n=40)及低信号组(n=20),对比患者手术前后肌瘤体积、缩小率、血流分级及疗效情况。结果手术前肌瘤体积为12.68(5.80,20.21)cm^(3),手术后12个月肌瘤体积为4.00(1.32,7.35)cm^(3),肌瘤体积缩小率为73.98(49.19,84.97)%。不同信号强度的血流分级之间差异有统计学意义(Z=15.579,P<0.05);不同信号组间的疗效差异有统计学意义(Z=18.327,P<0.001);不同血流等级间的疗效差异有统计学意义(Z=16.518,P<0.001)。Logistic回归分析显示血流情况(OR=2.819)及MR信号强度(OR=0.173)是患者微波消融疗效的影响因素(P<0.05)。结论血流情况及MR信号强度是微波消融治疗子宫肌瘤疗效的影响因素,可以用于预测消融子宫肌瘤的疗效。Objective To explore relationship between blood flow,magnetic resonance(MR)signal intensity and the efficacy of microwave ablation for uterine fibroids.Methods 64 patients with 79 uterine fibroids diagnosed by MR in Red Cross Hospital of Yulin City from July 2021 to June 2023 were selected and treated with microwave ablation.According to MR signal intensity,they were divided into high signal group(n=19),equal signal group(n=40)and low signal group(n=20).And then,volume,reduction rate,blood flow grade and curative effect of fibroids before and after operation were compared.Results The volume of fibroids before operation was 12.68(5.80,20.21)cm^(3),the volume of fibroids was 4.00(1.32,7.35)cm^(3) at 12 months after operation,and the volume reduction rate of fibroids was 73.98(49.19,84.97)%.There was statistically significant difference in the blood flow grades of different signal intensities(Z=15.579,P<0.05).There was statistically significant difference in efficacy between different signal groups(Z=18.327,P<0.001).There was statistically significant difference in efficacy between different blood flow grades(Z=16.518,P<0.001).Logistic regression analysis showed that blood flow(OR=2.819)and MR signal intensity(OR=0.173)were factors affecting the ablation effect of microwave ablation in patients(P<0.05).Conclusion Blood flow and MR signal intensity are factors affecting the efficacy of microwave ablation of uterine fibroids,which can be used to predict the efficacy of microwave ablation of uterine fibroids.

关 键 词：子宫肌瘤 超声血流成像 磁共振成像 微波消融术 

分 类 号：R737.33[医药卫生—肿瘤]