发酵技术在药食两用中药葛根中的应用研究进展  

Fermentation technology in application of Puerariae Lobatae Radix with medicinal and edible properties:a review

作　　者：管咏梅 李丽琴 张煜薇 陈丽梅[2] 董欢欢 朱卫丰 臧振中 GUAN Yong-mei;LI Li-qin;ZHANG Yu-wei;CHEN Li-mei;DONG Huan-huan;ZHU Wei-feng;ZANG Zhen-zhong(Key Laboratory of Modern Chinese Medicine Formulations of Ministry of Education,Jiangxi University of Chinese Medicine,Nanchang 330004,China;the Afiliated Hospital of Jiangxi University of Chinese Medicine,Nanchang 330004,China)

机构地区：[1]江西中医药大学现代中药制剂教育部重点实验室,江西南昌330004 [2]江西中医药大学附属医院,江西南昌330004

出　　处：《中国中药杂志》2024年第21期5797-5804,共8页China Journal of Chinese Materia Medica

基　　金：江西省重点研发计划项目(20224BBG71023);2023年度江西省研究生创新专项(YC2023-S764);2023年度江西中医药大学校级研究生创新专项(JZYC23S68);博士科研启动基金项目(2023WBZR007);中药学重点学科项目(2023jzzdxk016)。

摘　　要：葛根作为药食同源中药,具有解肌退热、生津止渴、通经活络等功效。现代发酵技术结合微生态学和现代生物工程,能够调控发酵过程,高效制备发酵产物。近年来,现代发酵技术在中药中的应用十分广泛,中药经发酵后可提高或改变疗效、减少毒性,扩大临床用药范围。该文根据葛根发酵相关研究现状,对葛根发酵方式、发酵菌种选择、发酵工艺、药理作用等方面进行综述,以期对葛根发酵的进一步深入研究和开发利用提供一定参考。Puerariae Lobatae Radix,as a traditional Chinese medicine(TCM)with both medicinal and edible properties,possesses effects such as relieving muscle tension and fever,generating fluids and quenching thirst,and unblocking the meridians and collaterals.Modern fermentation technology,combined with microecology and modern bioengineering,can regulate the fermentation process and efficiently produce fermentation products.In recent years,modern fermentation technology has been widely applied in TCM,enhancing or altering efficacy,reducing toxicity,and expanding the scope of clinical applications.This paper reviewed the current research on Puerariae Lobatae Radix fermentation,including fermentation methods,strain selection,fermentation processes,and pharmacological effects,with the aim of providing a reference for further in-depth research,development,and utilization of Puerariae Lobatae Radix fermentation.

关 键 词：葛根 发酵 菌种 药理变化 

分 类 号：R283[医药卫生—中药学]