胃转移性乳腺浸润性小叶癌1例并文献复习  

Invasive lobular carcinoma of the breast with gastric metastasis:a case report and literature review

作　　者：陈召旭 王笑 赵鹏[1] 赵静[1] 付广明[1] 王成勤[1,2] CHEN Zhaoxu;WANG Xiao;ZHAO Peng;ZHAO Jing;FU Guangming;WANG Chengqin(Department of Pathology,The Affiliated Hospital of Qingdao University,Qingdao 266000,China)

机构地区：[1]青岛大学附属医院病理科,山东青岛266000 [2]青岛大学医学部基础医学院病理学系,山东青岛266000

出　　处：《青岛大学学报（医学版）》2024年第5期775-777,共3页Journal of Qingdao University(Medical Sciences)

基　　金：山东省自然科学基金面上项目(ZR2022MH206)。

摘　　要：目的探讨胃转移性乳腺浸润性小叶癌(ILC)的临床病理特征及诊断要点。方法分析1例胃转移性ILC病人的临床病理特征、免疫表型及临床表现,并复习相关文献。结果本文病人既往有胃低分化腺癌病史,1年后发现左乳包块,经穿刺活检诊断为ILC。结合病史、胃黏膜和乳房穿刺活检以及免疫组织化学检查结果,最终诊断为胃转移性ILC。结论ILC胃转移较为罕见。当有ILC病史的病人出现胃低黏附性癌且不伴有原位癌时,应考虑ILC胃转移的可能性,并可通过胃镜检查、活检及免疫组织化学染色加以鉴别。Objective To investigate the clinicopathological features and key diagnostic points of invasive lobular carcinoma(ILC)of the breast with gastric metastasis.Methods One ILC patient with gastric metastasis was analyzed in terms of clinicopathological features,immunophenotypes,and clinical manifestations,and related articles were reviewed.Results A female patient,aged 45 years,who had a previous history of poorly differentiated gastric adenocarcinoma was found to have a mass in the left breast one year later and was diagnosed with ILC by aspirationbiopsy.Based on medical history,aspirationbiopsy of gastric mucosa and breast,and immunohistochemistry,the patient was finally diagnosed with ILC with gastric metastasis.Conclusion ILC with gastric metastasis is relatively rare.The possibility of gastric metastasis of ILC should be considered when a patient with the history of ILC is found to have low-adhesion gastric carcinoma without carcinoma in situ,and gastroscopy,biopsy,and immunohistochemical staining can be used for differential diagnosis.

关 键 词：乳腺肿瘤 肿瘤转移 胃肿瘤 诊断 鉴别 免疫组织化学 病例报告 

分 类 号：R737.9[医药卫生—肿瘤]