VR模拟飞行诱发试验在脑电监测中的应用研究  

Applications of VR simulated fl ight activation tests in EEG examination

作　　者：陈泽 王晓丽 高玉雯 温文颢 王则直 张歆博 潘远航 刘永红 CHEN Ze;WANG Xiaoli;GAO Yuwen;WEN Wenhao;WANG Zezhi;ZHANG Xinbo;PAN Yuanhang;LIU Yonghong(Department of Neurology,Xijing Hospital,Air Force Medical University,PLA,Xi'an 710032,China)

机构地区：[1]空军军医大学西京医院神经内科,西安710032

出　　处：《空军航空医学》2024年第5期385-388,共4页AVIATION MEDICINE OF AIR FORCE

基　　金：国家重点研发计划(2022YFC2503806);国家自然科学基金(82372033);陕西省重点研发计划(2023-YBSF-199)。

摘　　要：目的 探究虚拟现实(virtual reality,VR)模拟飞行环境诱发试验在脑电图监测中的有效性与安全性。方法 根据飞行人员职业环境特点,设计包含飞机起降,编队飞行,机动飞行,雪景飞行等内容的VR模拟飞行眼镜(专利号:ZL202320554741.9),于2020年9月—2023年9月对60名飞行人员、60名健康志愿者及100例癫痫患者给予视频脑电图监测并进行VR模拟诱发试验,通过比较不同诱发试验的阳性检出率来说明VR模拟诱发试验的有效性。结果 100例癫痫患者中,有2例闪光刺激阳性(2%),2例过度换气阳性(2%),3例VR模拟飞行试验阳性(3%);60名飞行人员和60名健康受试者的闪光刺激与过度换气均为阴性。此外,60名飞行人员中1名VR模拟飞行试验出现头晕;60名健康受试者中7名VR模拟飞行试验中感到头晕,1名因头晕、恶心、呕吐中断试验。结论 VR模拟诱发试验安全性良好,可以诱发癫痫样放电,未来需要更大样本的研究验证其在飞行人员脑电监测期间使用的可行性。Objective To investigate the effectiveness and safety of VR(virtual reality)simulated flight environment provocation tests in electroencephalogram(EEG)monitoring.Methods Based on the occupational environmental characteristics of flight personnel,this study designed VR-simulated flight glasses(Patent No.ZL202320554741.9)incorporating such scenarios as aircraft takeoff and landing,formation flight,maneuvering flight,and snow flight.From September 2020 to September 2023,60 flight personnel,60 healthy volunteers,and 100 patients with epilepsy underwent video-EEG monitoring and VR-simulated induction tests.The effectiveness of the VR simulated induction test was demonstrated by comparing the positive detection rates in different induction tests.Results Among the 100 patients with epilepsy,2(2%)were positive for intermittent photic stimulation(IPS),2(2%)for hyperventilation(HV),and 3(3%)for the VR simulated flight test.Both IPS and HV were negative in the 60 flight personnel and 60 healthy subjects.Additionally,1 of the 60 flight personnel experienced dizziness during the VR-simulated flight test,while 7 of the 60 healthy subjects felt dizzy during the test,with 1 discontinuing the test due to dizziness,nausea,and vomiting.Conclusion The VR simulated provocation tests have demonstrated good safety and the ability to induce epileptiform discharges.However,more studies with larger sample sizes are needed to validate the feasibility of using this approach during EEG monitoring of aircrew members.

关 键 词：癫痫 脑电图 诱发试验 VR模拟飞行 癫痫样放电 

分 类 号：R741.04[医药卫生—神经病学与精神病学]