13649例中国东南部地区腮腺肿瘤构成比分析  

Clinical analysis of 13649 cases of parotid gland tumors in southeast China

作　　者：顾挺[1] 孙晶晶[1] 王瑜 田臻[1] 王丽珍[1] 胡宇华[1] 夏荣辉[1] 李江[1] 张春叶[1] GU Ting;SUN Jing-jing;WANG Yu;TIAN Zhen;WANG Li-zhen;HU Yu-hua;XIA Rong-hui;LI Jiang;ZHANG Chun-ye(Department of Oral Pathology,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,College of Stomatology,Shanghai Jiao Tong University,National Center for Stomatology,National Clinical Research Center for Oral Diseases,Shanghai Key Laboratory of Stomatology,Research Unit of Oral and Maxillofacial Regenerative Medicine,Chinese Academy of Medical Sciences.Shanghai 200011,China)

机构地区：[1]上海交通大学医学院附属第九人民医院口腔病理科,上海交通大学口腔医学院,国家口腔医学中心,国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室,中国医学科学院口腔颌面再生医学创新单元,上海200011

出　　处：《中国口腔颌面外科杂志》2024年第6期590-596,共7页China Journal of Oral and Maxillofacial Surgery

基　　金：国家自然科学基金(82141108,82103405);上海交通大学医学院附属第九人民医院临床研究助推计划(JYLJ202119)。

摘　　要：目的:分析腮腺内肿瘤的病理类型及构成比,为流行病学提供数据支持。方法:收集2005年1月—2022年12月上海交通大学医学院附属第九人民医院口腔病理科确诊为腮腺内的肿瘤病例,分析患者性别、年龄、病理类型等特点。结果:共收集13649例腮腺内肿瘤病例。患者年龄1~104岁,高峰年龄51~60岁,男女之比为1.3∶1。其中,良性11008例(80.7%),中间型/恶性2641例(19.3%)。上皮源性肿瘤12856例(94.2%),软组织肿瘤454例(3.3%),淋巴造血系统来源肿瘤339例(2.5%)。原发唾液腺肿瘤12228例,其中恶性占15.9%(1939/12228),良性占84.1%(10289/12228)。多形性腺瘤和癌在多形性腺瘤中分别是良、恶性肿瘤最常见的类型,转移性肿瘤以鼻咽淋巴上皮癌转移至腮腺最常见;神经鞘膜瘤是最常见的软组织肿瘤,黏膜相关淋巴组织结外边缘区淋巴瘤是腮腺淋巴造血系统肿瘤中最常见的肿瘤类型。结论:中国东南部地区腮腺内肿瘤,多形性腺瘤和癌在多形性腺瘤中是最常见的良、恶性肿瘤,神经鞘膜瘤和MALT淋巴瘤分别是最常见的软组织肿瘤和淋巴造血系统肿瘤。PURPOSE:To analyze the pathological types and composition ratios of tumors within the parotid gland in order to provide data for epidemiological support.METHODS:Patients diagnosed with parotid tumors were recruited from Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine between 2005 to 2022.The patient sex,age and tumor type were collected.RESULTS:Totally 13649 cases were enrolled in this study.The patients’age ranged from 1 to 104 years,with the peak age occurring in the sixth decade.The male to female ratio was 1.3∶1.Among of them,totally 11008 were benign tumors(80.7%),and 2641(19.3%)were intermediate/malignant tumors.A total of 12856 cases(94.2%)originated from epithelium,while 454 cases(3.3%)from soft tissues and 339 cases(2.5%)from haematopoietic and lymphoid tissues.Among 12228 cases of primary salivary gland tumors,totally 10289(84.1%)of them were benign and 1939(15.9%)were malignant.Pleomorphic adenoma and carcinoma ex pleomorphic adenoma were the most common benign and malignant subtype,respectively.Nasopharyngeal lymphoepithelial carcinoma was the most prevalent among different types of metastatic tumors to the parotid gland.The most common soft tissue and haematopoietic and lymphoid tissue tumor in the parotid gland were Schwannoma and extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue lymphoma(MALT lymphoma).CONCLUSIONS:In southeastern region of China,parotid tumors,pleomorphic adenoma and carcinoma ex pleomorphic adenoma are the most common benign and malignant tumors of the parotid gland.The most prevalent soft tissue tumors and lymphoid hematopoietic system tumors are Schwannoma and MALT lymphoma,respectively.

关 键 词：腮腺肿瘤 肿瘤构成 流行病学 中国东南部 

分 类 号：R739.8[医药卫生—肿瘤]