左侧上颌骨牙源性影细胞癌1例报告及文献复习  

Ghost cell odontogenic carcinoma in the left maxilla:a case report and literature review

作　　者：郭小冬 苏勤军[2] 王环环 何倩倩 陈哲宇 姬菩忠 马迎春[2] 杨艳丽 GUO Xiao-dong;SU Qin-jun;WANG Huan-huan;HE Qian-qian;CHEN Zhe-yu;JI Pu-zhong;MA Ying-chun;YANG Yan-li(Gansu University of Chinese Medicine,Lanzhou 730000;Department of Pathology,The 940 Hospital of the Joint Logistics Support Force of the People's Liberation Army,Lanzhou 730050;Northwest Minzu University,Lanzhou 730030,Gansu Province,China)

机构地区：[1]甘肃中医药大学,甘肃兰州730000 [2]中国人民解放军联勤保障部队第940医院病理科,甘肃兰州730050 [3]西北民族大学,甘肃兰州730030

出　　处：《中国口腔颌面外科杂志》2024年第6期618-621,共4页China Journal of Oral and Maxillofacial Surgery

基　　金：甘肃省科技计划资助(省青年科技基金,22JR5RA022);中国人民解放军联勤保障部队第940医院院内课题(2021yxky049)。

摘　　要：牙源性影细胞癌(ghost cell odontogenic carcinoma,GCOC)是起源于颌骨的罕见恶性肿瘤,其在临床与影像上可表现出与良性牙源性肿瘤不同的恶性特征,例如肿瘤体积大、伴有周围骨质破坏等,但不具备特异性,因此往往依靠病理形态学确诊。GCOC的特征在于异常角质化的影细胞、小的基底样细胞和类牙本质沉积。准确诊断该病有重要的临床意义并有利于患者预后。本文报告1例左侧上颌骨GCOC,并结合相关文献进行复习。Ghost cell odontogenic carcinoma(GCOC)is a rare malignant tumor originating in the jawbone,which can exhibit clinically and radiographically malignant features distinct from benign odontogenic tumors,such as large tumor size and adjacent bone destruction,but these features lack specificity;therefore,diagnosis often relies on pathological morphology.Characterized by abnormal keratinized ghost cells,small basaloid cells,and dentin-like deposits,accurate identification of GCOC holds significant clinical importance and is beneficial for patient prognosis.This paper reported a case of GCOC in the left maxilla and reviewed the relevant literature.

关 键 词：上颌骨肿瘤 牙源性肿瘤 牙源性影细胞癌 病理特征 

分 类 号：R739.8[医药卫生—肿瘤]