术前进行定向磁化率成像对胶质瘤恶性程度与预后的诊断价值  

The preoperative diagnostic value of quantitative susceptibility mapping technology for the malignancy and prognosis of glioma

作　　者：王世雄 田继辉[1] 陈鹏飞[1] WANG Shixiong;TIAN Jihui;CHEN Pengfei(Department of Neurosurgery,General Hospital of Ningxia Medical University,Yinchuan 750004,China;Department of Clinical Medicine,Ningxia Medical University,Yinchuan 750004,China)

机构地区：[1]宁夏医科大学总医院神经外科,宁夏银川750004 [2]宁夏医科大学研究生院,宁夏银川750004

出　　处：《宁夏医学杂志》2024年第11期937-940,F0002,共5页Ningxia Medical Journal

基　　金：宁夏重点研发计划项目(2022BEG03081);宁夏重点研发项目(2023BEG2009);宁夏医科大学校级课题项目(XJ2023036)。

摘　　要：目的 探讨定量磁化率成像技术(QSM)对颅内胶质瘤恶性程度的术前诊断价值。方法 收集12例因脑胶质瘤行首次手术治疗,且术前接受定量磁化率成像检查的患者影像学数据。测量术前目标区域磁化率高低差异,与术后病理特征进行相关性分析。结果 ROI区域和正常Control区域的磁化率值不同,即肿瘤改变了局部的磁化率值;高级别、低级别胶质瘤之间ROI和Control区域之间磁化率差值比较有统计学意义(P<0.05);磁化率差值对高级别胶质瘤具有一定的诊断价值。结论 定量磁化率成像技术有助于在术前提高高级别胶质瘤的检出率,为胶质瘤术前诊断提供一定的参考价值。Objective To explore the preoperative diagnostic value of quantitative susceptibility mapping(QSM)for the malignancy of intracranial gliomas.Methods The imaging data was collected from 15 patients with gliomas who underwent their first surgical treatment and underwent preoperative QSM examination.The difference in magnetic susceptibility of the target area before surgery was measure and its correlation with postoperative pathological features was analyzed.Results The magnetic susceptibility values of the ROI region and the normal control region were different,the tumor changed the local magnetic susceptibility values;The difference in magnetic susceptibility between ROI and control regions between high-grade and low-grade gliomas was statistically significant(P<0.05);The difference in magnetic susceptibility has certain diagnostic value for high-grade gliomas.Conclusion QSM technology can improve the detection rate of high-grade gliomas before surgery,providing certain reference value for preoperative diagnosis of gliomas.

关 键 词：胶质瘤 定量磁化率成像 恶性程度 铁代谢 诊断价值 

分 类 号：R739.41[医药卫生—肿瘤]