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作 者:张淼[1] 庄友梅[1] 刘洁[1] ZHANG Miao;ZHUANG Youmei;LIU Jie(Department of Stomatology,Xinjiang Uiger Municipal People's Hospital,Urumqi 830001,Xinjiang,China)
机构地区:[1]新疆维吾尔自治区人民医院口腔科,新疆乌鲁木齐830001
出 处:《中国美容医学》2024年第12期175-178,共4页Chinese Journal of Aesthetic Medicine
基 金:院内课题(名称:炎性复合体在慢性牙周炎中的表达调控研究,编号:20190404)。
摘 要:目的:探讨Er︰YAG激光辅助牙周基础治疗对慢性牙周炎(Chronic periodontitis,CP)患者临床症状的改善作用。方法:选取2019年1月-2022年4月新疆维吾尔自治区人民医院收治的106例CP患者,采用随机数字表法划分成常规组(n=53)和研究组(n=53)。常规组接受牙周基础治疗,研究组在常规组基础上接受Er:YAG激光治疗。比较两组疗效、不良反应发生情况,以及治疗前、治疗后3个月牙周临床指标[探诊深度(Probing depth,PD)、牙龈指数(Gingival index,GI)、临床附着丧失(Clinical attachment loss,CAL)]、龈沟液炎性因子水平[肿瘤坏死因子-α(Tumor necrosis factor-α,TNF-α)、白介素-6(Interleukin-6,IL-6)]。结果:研究组治疗总有效率92.45%,高于常规组的75.47%(P<0.05);治疗后3个月,两组PD、GI、CAL均降低,且研究组低于常规组(P<0.05);治疗后3个月,两组患者龈沟液TNF-α、IL-6水平均下降,且研究组较常规组低(P<0.05);研究组不良反应发生率为13.21%,常规组不良反应发生率为7.55%,组间差异无统计学意义(P>0.05)。结论:Er:YAG辅助牙周基础治疗能有效缓解CP患者临床症状,改善牙周状况,减轻牙周炎症反应,且安全性高。Objective To investigate the improvement of clinical symptoms in patients with chronic periodontitis(CP)with Er:YAG assisted periodontal basal therapy.Methods A total of 106 CP patients admitted to Xinjiang Uiger Municipal People's Hospital from January 2019 to April 2022 were selected and divided into conventional group(n=53)and study group(n=53)by random number table method.The conventional group received periodontal basal therapy,and the study group received Er:YAG treatment on the basis of the conventional group.The efficacy,occurrence of adverse reactions,before treatment and three months after treatment the clinical indicators[probing depth(PD),gingival index(GI),clinical attachment loss(CAL)],and inflammatory factors in gingival creval fluid[Tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)]of the two groups were compared.Results The total effective rate of the study group was 92.45%higher than that of the conventional group 75.47%(P<0.05).At three months after treatment,PD,GI and CAL were decreased in the study group and the conventional group,and the study group was lower than the conventional group(P<0.05).After three months of treatment,the levels of TNF-αand IL-6 in gingival crevicular fluid in two groups were decreased,and the levels in the study group were lower than those in the conventional group(P<0.05).The incidence of adverse reactions was 13.21%in the study group and 7.55%in the conventional group,with no significant difference between the groups(P>0.05).Conclusion Er:YAG assisted periodontal basal therapy can effectively relieve the clinical symptoms of CP patients,improve the periodontal condition,reduce periodontal inflammation,and has good safety.
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