高场磁共振多b值弥散加权成像对肝细胞癌与肝血管瘤的鉴别诊断价值分析  

Analysis of the Differential Diagnostic Value of High-field Magnetic Resonance Multi b-value Diffusion-weighted Imaging for Hepatocellular Carcinoma and Hepatic Hemangioma

作　　者：郭凯[1] 孙勇[1] 杨明[1] 丁会[1] GUO Kai;SUN Yong;YANG Ming(Zhoukou Central Hospital,Zhoukou,466000)

机构地区：[1]河南省周口市中心医院,466000

出　　处：《实用癌症杂志》2024年第12期2048-2051,共4页The Practical Journal of Cancer

摘　　要：目的分析高场磁共振(MRI)多b值弥散加权成像(DWI)对肝细胞癌与肝血管瘤中的鉴别诊断价值。方法选取行高场MRI-DWI检查的109例患者,所有患者病情经病理检查明晰,43例肝细胞癌患者划入观察组,66例肝血管瘤患者划入对照组,对比两组不同b值下的表观弥散系数(ADC)值;另绘制受试者工作曲线(ROC),分析不同b值下ADC值鉴别诊断肝细胞癌与肝血管瘤的效能。结果b值为50 s/mm^(2)、400 s/mm^(2)、1000 s/mm^(2)时,观察组的ADC值分别为(2.09±0.42)×10^(-3)/mm^(2)/s、(1.72±0.36)×10^(-3)/mm^(2)/s、(1.39±0.28)×10^(-3)/mm^(2)/s,均低于对照组的(2.45±0.57)×10^(-3)/mm^(2)/s、(2.16±0.45)×10^(-3)/mm^(2)/s、(1.88±0.47)×10^(-3)/mm^(2)/s,有统计学差异(P<0.05);ROC结果显示:当b值在1000 s/mm^(2)时,ADC值鉴别诊断肝细胞癌与肝血管瘤的曲线下面积(AUC)、敏感度、特异度最高,分别为0.816、90.70%、72.70%。结论高场MRI-DWI能够有效鉴别诊断出肝细胞癌与肝血管瘤,且b值越大,诊断效果越强,具有一定的应用价值。Objective To analyze the differential diagnostic value of high field magnetic resonance imaging(MRI)multi b-value diffusion-weighted imaging(DWI)in hepatocellular carcinoma and hepatic hemangioma.Methods A total of 109 patients who underwent high-field MRI-DWI examination were selected,and their conditions were clarified through pathological examination.43 patients with hepatocellular carcinoma were assigned to the observation group,and 66 patients with hepatic hemangioma were assigned to the control group.The apparent diffusion coefficient(ADC)values under different b values were compared between the 2 groups;Additionally,draw a receiver operating curve(ROC)to analyze the effectiveness of ADC values in differential diagnosis of hepatocellular carcinoma and hepatic hemangioma under different b values.Results When the result b value was 50 s/mm^(2),400 s/mm^(2),and 1000 s/mm^(2),the ADC values of the observation group were(2.09±0.42),respectively×10^(-3)/mm^(2)/s,(1.72±0.36)×10^(-3)/mm^(2)/s,(1.39±0.28)×10^(-3)/mm^(2)/s,all lower than the control group's(2.45±0.57)×10^(-3)/mm^(2)/s,(2.16±0.45)×10^(-3)/mm^(2)/s,(1.88±0.47)×10^(-3)/mm^(2)/s,with statistical difference(P<0.05);The ROC results showed that when the b value was 1000 s/mm^(2),the area under the curve(AUC),sensitivity,and specificity of ADC value for differential diagnosis of hepatocellular carcinoma and hepatic hemangioma were the highest,with values of 0.816,90.70%,and 72.70%,respectively.Conclusion High field MRI-DWI can effectively differentiate and diagnose hepatocellular carcinoma and hepatic hemangioma,and the larger the b-value,the stronger the diagnostic effect,which has certain practical value.

关 键 词：肝细胞癌 肝血管瘤 高场磁共振多b值弥散加权成像 诊断 

分 类 号：R735.7[医药卫生—肿瘤]