皮肤镜联合Mohs手术治疗皮肤基底细胞癌的效果  

Therapeutic effects of dermoscopy combined with Mohs surgery on basal cell carcinoma

作　　者：朱莹[1] 乔改红[1] Zhu Ying;Qiao Gaihong(Department of Plastic Surgery,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)

机构地区：[1]郑州大学第一附属医院整形外科,郑州450000

出　　处：《中国实用医刊》2024年第20期1-4,共4页Chinese Journal of Practical Medicine

摘　　要：目的分析皮肤镜联合显微描记(Mohs)手术治疗皮肤基底细胞癌的临床效果。方法队列研究。抽取2020年4月至2023年4月郑州大学第一附属医院收治的皮肤基底细胞癌患者68例,按随机数字表法分为皮肤镜组和Mohs术组,每组34例。Mohs术组采用Mohs手术,皮肤镜组采用皮肤镜联合Mohs手术。对比两组围术期指标、肿瘤相关指标、扩切2 cm时切缘性质、复发率及治疗满意度。结果皮肤镜组送检次数少于Mohs术组,手术时间短于Mohs术组,病理费用少于Mohs术组(P<0.05)。皮肤镜组术后皮肤缺损面积小于Mohs术组,首次切缘距离肿瘤边缘最大、最小距离均短于Mohs术组(P均<0.05)。皮肤镜组扩切2 cm时切缘阳性率(8.82%,3/34)低于Mohs术组(29.41%,31/34),阴性率(91.18%,10/34)高于Mohs术组(70.59%,24/34),P<0.05。皮肤镜组复发率(2.94%,1/34)低于Mohs术组(23.53%,8/34),P<0.05。皮肤镜组治疗总满意度(97.06%,33/34)高于Mohs术组(76.47%,26/34),P<0.05。结论皮肤镜联合Mohs手术治疗皮肤基底细胞癌,可减少送检次数和病理费用,缩小皮肤缺损面积,提高扩切切缘阴性率,并可降低复发率,改善预后,提高患者治疗满意度。Objective To investigate the therapeutic effect of dermoscopy combined with Mohs surgery on basal cell carcinoma.Methods A total of 68 patients with basal cell carcinoma treated in the First Affiliated Hospital of Zhengzhou University from April 2020 to April 2023 were selected for the cohort study.And they were divided into dermoscopy group and Mohs surgery group using a random number table method,with 34 cases in each group.The Mohs surgery group was treated by Mohs surgery,and the dermoscopy group was treated by dermoscopy combined with Mohs surgery.The perioperative indicators,tumor related indicators,the nature of the resection margin when the resection was expanded by 2 cm,the recurrence rate,and the treatment satisfaction were compared between the two groups.Results The dermoscopy group required less frequency of pathological examination,shorter operation duration and less pathological cost compared with the Mohs surgery group(P<0.05).The area of postoperative skin defect in the dermoscopy group was smaller than that in the Mohs surgery group,while the maximum and minimum distances between the first resection margin and the tumor edge in the dermoscopy group were shorter than those in the Mohs surgery group(all P<0.05).The positive rate of resection margin expanded by 2 cm in the dermoscopy group(8.82%,3/34)was lower than that in the Mohs surgery group(29.41%,31/34),and the negative rate in the dermoscopy group(91.18%,10/34)was higher than that in the Mohs surgery group(70.59%,24/34),P<0.05.The recurrence rate of the dermoscopy group(2.94%,1/34)was lower than that of the Mohs surgery group(23.53%,8/34),P<0.05.The total treatment satisfaction of the dermoscopy group(97.06%,33/34)was higher than that of the Mohs surgery group(76.47%,26/34),P<0.05.Conclusions Dermoscopy with Mohs surgery in the treatment basal cell carcinoma can reduce the frequency of pathological examination and cost,reduce the area of skin defect,improve the negative rate of expanded resection margin,reduce the recurrence rate,improve the

关 键 词：皮肤基底细胞癌 皮肤镜 Mohs手术 

分 类 号：R739.5[医药卫生—肿瘤]