乳果糖联合复方聚乙二醇在便秘患者肠道准备中的应用  

作　　者：施惠海[1] 马佳林 周春晓 

机构地区：[1]南京医科大学附属苏州医院,215002

出　　处：《浙江临床医学》2024年第11期1714-1716,共3页Zhejiang Clinical Medical Journal

摘　　要：目的探讨乳果糖在便秘患者肠道准备中的效果。方法选取于2021年6月至2023年8月本院接受治疗的200例便秘患者。随机分为观察组和对照组,每组100例。观察组采用乳果糖联合复方聚乙二醇电解质散(PEGP)进行肠道准备,对照组仅使用PEGP,对比两组患者的肠道准备有效率、耐受率和不良反应,并分析血钾水平。结果观察组肠道准备有效率为90%,对照组为64%,两组比较差异有统计学意义(P<0.05);观察组的耐受率为78%,而对照组为43%,差异有统计学意义(P<0.05);观察组的不良反应率为24%,对照组为21%,差异无统计学差异(P>0.05);两组患者检查前后血钾无明显改变(P>0.05)。结论乳果糖能够改善便秘患者的肠道准备效果,提高耐受性,且不影响血钾水平。Objective To investigate the effect of lactulose in bowel preparation for constipated patients.Methods A comparison was made between 200 constipated patients at the main branch of Suzhou Municipal Hospital from June 2021 to August 2023.Patients were randomly divided into a treatment group and a control group.The treatment group used lactulose in combination with polyethylene glycol electrolyte powder(PEGP)for bowel preparation,while the control group used only PEGP.The bowel preparation effectiveness,tolerance,and adverse reactions of the two groups were compared,and blood potassium levels were analyzed.Results The bowel preparation effectiveness rate in the treatment group was 90%,which was significantly higher than the 64%in the control group(P<0.05).The tolerance rate in the treatment group was 78%,higher than the 43%in the control group(P<0.05).The adverse reaction rates in the treatment and control groups were 24%and 21%,respectively,with no significant difference(P>0.05).There was no significant change in blood potassium levels before and after the examination in both groups(P>0.05).Conclusion Lactulose can improve the bowel preparation effect for constipated patients,enhance tolerance,and does not affect blood potassium levels.

关 键 词：乳果糖 便秘 肠道准备 

分 类 号：R574.62[医药卫生—消化系统]