乳腺癌改良根治术后即刻行背阔肌肌皮瓣Ⅰ期乳房重建术对乳腺癌患者围术期指标及生活质量的影响  

Impact of Immediate StageⅠBreast Reconstruction with Latissimus Dorsi Myocutaneous Flap after Modified Radical Mastectomy for Breast Cancer on Perioperative Indicators and Quality of Life of Breast Cancer Patients

作　　者：艾小红[1] 艾一凡 赵鹏 AI Xiaohong;AI Yifan;ZHAO Peng(Department of Breast,Baiyin First People's Hospital of Gansu Province,Baiyin 730900,China;Department of Rehabilitation,Baiyin First People's Hospital of Gansu Province,Baiyin 730900,China;The Third Department of General Surgery,Third People's Hospital of Gansu Province,Lanzhou 730000,China)

机构地区：[1]甘肃省白银市第一人民医院乳腺科,甘肃白银730900 [2]甘肃省白银市第一人民医院康复科,甘肃白银730900 [3]甘肃省第三人民医院普外三科,甘肃兰州730000

出　　处：《反射疗法与康复医学》2024年第13期83-86,106,共5页Reflexology And Rehabilitation Medicine

基　　金：甘肃省白银市科技计划项目(2022-3-10Y)。

摘　　要：目的分析乳腺癌改良根治术后即刻行背阔肌肌皮瓣Ⅰ期乳房重建术对乳腺癌患者围术期指标与生活质量的影响。方法回顾性分析2021年3月—2023年10月于白银市第一人民医院及甘肃省第三人民医院接受乳腺癌改良根治术治疗的140例乳腺癌患者的临床资料,根据手术方式不同将其分为对照组和试验组,每组70例。对照组患者接受乳腺癌改良根治术治疗,试验组患者在对照组基础上接受背阔肌肌皮瓣Ⅰ期乳房重建术治疗。比较两组的围术期指标、并发症发生情况、生活质量、应激反应、焦虑抑郁情况。结果术前,两组生活质量、应激反应、焦虑抑郁情况比较,组间差异无统计学意义(P>0.05);两组开始辅助化疗时间、术后引流时间、并发症发生率比较,组间差异无统计学意义(P>0.05);试验组术中出血量多于对照组,手术时间长于对照组,组间差异有统计学意义(P<0.05);术后6个月,试验组乳腺癌患者生命质量测定量表中功能情况、生理状况、情感状况、社会家庭状况、附加关注评分均高于对照组,组间差异有统计学意义(P<0.05);术后1 d,试验组超氧化物歧化酶水平高于对照组,皮质醇水平低于对照组,组间差异有统计学意义(P<0.05);术后1 d,试验组汉密尔顿焦虑量表、汉密尔顿抑郁量表评分分别为(10.36±2.14)分、(10.95±2.39)分,均低于对照组的(15.42±3.51)分、(15.64±3.92)分,组间差异有统计学意义(P<0.05)。结论乳腺癌改良根治术后即刻行背阔肌肌皮瓣Ⅰ期乳房重建术治疗,会增加患者术中出血量与手术时间,可改善患者生活质量及应激反应,减轻其焦虑抑郁情况。Objective Analyze the impact of immediate stage I breast reconstruction with latissimus dorsi myocutaneous flap after modified radical mastectomy for breast cancer on perioperative indicators and quality of life of breast cancer patients.Methods A retrospective analysis was conducted on the clinical data of 140 breast cancer patients who received modified radical mastectomy in Baiyin First People's Hospital of Gansu Province and Third People's Hospital of Gansu Province from March 2021 to October 2023.According to different surgical methods,they were divided into a control group and an experimental group,with 70 cases in each group.Patients in the control group received modified radical mastectomy for breast cancer treatment.Patients in the experimental group received stage I breast reconstruction with latissimus dorsi myocutaneous flap on the basis of the control group.The perioperative indicators,occurrence of complications,quality of life,stress response,and anxiety and depression were compared between the two groups.Results Before surgery,the quality of life,stress response,and anxiety and depression were compared between the two groups,and the differences between the groups were no statistically significant(P>0.05);the start time of adjuvant chemotherapy,postoperative drainage time and complication rate were compared between the two groups,and the differences between the groups were no statistically significant(P>0.05);in the experimental group,the intraoperative blood loss was more than that in the control group,and the operation time was longer than that in the control group,and the differences between the groups were statistically significant(P<0.05);six months after surgery,the scores of functional status,physiological status,emotional status,social and family status,and additional attention in the Functional Assessment of Cancer Therapy-Breast in the experimental group were all higher than those in the control group,and the differences between the groups were statistically significant(P<0.05);one day af

关 键 词：乳腺癌 背阔肌肌皮瓣Ⅰ期乳房重建术 乳腺癌改良根治术 围术期指标 生活质量 

分 类 号：R737.9[医药卫生—肿瘤]