3D-PDUS血管参数定量评估子宫肌瘤HIFU消融效果的价值  

Value of 3D-PDUS Vascular Parameters Quantitatively Evaluate HIFU Ablation Effect on Hysteromyoma

作　　者：王芳[1] 邹建中[1] 任丽 罗孝勇[2] Wang Fang;Zou Jianzhong;Ren Li;Luo Xiaoyong(State Key Laboratory of Ultrasound in Medicine and Engineering,College of Biomedical Engineering,Chongqing Medical University,Chongqing 400016,China;Department of Ultrasound,Suining Central Hospital,Suining,Sichuan 629000,China)

机构地区：[1]重庆医科大学超声医学工程国家重点实验室生物工程学院,重庆市400016 [2]遂宁市中心医院超声科,四川省遂宁市629000

出　　处：《中国超声医学杂志》2024年第11期1289-1292,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的观察三维能量多普勒超声(3D-PDUS)血管参数定量评估子宫肌瘤高强度聚焦超声(HIFU)消融效果的价值。方法纳入HIFU消融治疗的子宫肌瘤67个,根据磁共振T_(1)加权成像(MRI T_(1)WI)增强肌瘤强化程度分为轻度强化组与明显强化组,进行3D-PDUS扫查获取肌瘤体积及血管参数[血管指数(VI)、血流指数(FI)、血管化血流指数(VFI)],并计算HIFU消融后VI、FI、VFI下降率,比较组间差异、消融前后的变化情况以及与HIFU消融效果的相关性。结果MRI T_(1)WI强化程度越高,VI及VFI越高,消融后VI、FI、VFI均降低,P<0.05。轻度强化组中,肌瘤体积与HIFU消融率及能效因子(EEF)相关性较高,明显强化组中,VI、FI、VFI下降率与HIFU消融率及EEF显著相关,高消融肌瘤(消融率≥70%)的VI、FI、VFI下降率高于低消融肌瘤(消融率<70%),P<0.05。结论3D-PDUS血管参数能够定量评估子宫肌瘤HIFU消融前后的血流变化情况,肌瘤体积及VI、FI、VFI下降率与HIFU消融效果存在相关性,3D-PDUS评估子宫肌瘤HIFU消融效果有一定价值。Objective To observe the value of using three-dimensional power Doppler ultrasound(3D-PDUS)vascular parameters in the quantitative assessment of the efficacy of high-intensity focused ultrasound(HIFU)ablation for hysteromyoma.Methods Sixty-seven hysteromyomas treated with HIFU ablation were included in the study.The hysteromyomas were categorized into two groups based on the degree of enhancement on magnetic resonance T_(1)-weighted imaging(MRI T_(1)WI):a mild enhancement group and a significant enhancement group.3D-PDUS was used to scan the hysteromyoma,obtaining hysteromyoma volume and vascular parameters[vascularization index(VI),flow index(FI),vascularization-flow index(VFI)].The reduction rates of VI,FI,and VFI after ablation were calculated.Differences between the groups,changes before and after HIFU ablation,and the correlation with HIFU ablation efficacy were compared.Results The higher the enhancement on MRI T_(1)WI,the higher the VI and VFI.After HIFU ablation,VI,FI,and VFI all decreased,with P<0.05.In the mild enhancement group,hysteromyoma volume had a higher correlation with HIFU ablation rate and energy efficiency factor(EEF).In the significant enhancement group,the reduction rates of VI,FI,and VFI were significantly correlated with HIFU ablation rate and EEF.The reduction rates of VI,FI,and VFI in high-ablation hysteromyoma(ablation rate≥70%)were higher than those in low-ablation hysteromyoma(ablation rate<70%),with P<0.05.Conclusions 3D-PDUS vascular parameters can quantitatively assess the changes in blood perfusion before and after HIFU ablation of hysteromyoma.The reduction rates of hysteromyoma volume,VI,FI,and VFI are correlated with HIFU ablation efficacy,suggesting that 3D-PDUS has a certain value in evaluating the efficacy of HIFU ablation for hysteromyoma.

关 键 词：三维能量多普勒超声 HIFU消融效果 子宫肌瘤 血管参数 

分 类 号：R737.33[医药卫生—肿瘤] R445.1[医药卫生—临床医学]