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作 者:钟志强 王智源 刘洋 ZHONG Zhiqiang;WANG Zhiyuan;LIU Yang(Department of Stomatology,Zhoukou Traditional Chinese Medicine Hospital,Zhoukou Henan 466000,China)
出 处:《临床研究》2024年第12期73-76,共4页Clinical Research
摘 要:目的浅析超声引导下口腔颌面-颈部脉管畸形聚桂醇硬化介入治疗的临床效果。方法选取2021年10月至2023年10月周口市中医院收入的62例口腔颌面-颈部脉管畸形患者,依据数字表法随机分为对照组与观察组,各31例,对照组接受平阳霉素介入治疗,观察组接受聚桂醇硬化介入治疗,比较两组患者治疗次数、硬化剂使用量、术后疼痛程度、外观满意度、治疗效果、炎症因子、瘤腔最大径及不良反应。结果观察组患者治疗后瘤腔最大径、术后疼痛评分、硬化剂使用量均低于对照组,差异有统计学意义(P<0.05);观察组患者治疗有效率(93.55%)高于对照组(74.19%)、外观满意度(90.32%)高于对照组(67.74%),差异有统计学意义(P<0.05);观察组患者治疗后炎症因子指标均低于对照组,差异有统计学意义(P<0.05);观察组患者不良反应发生率(12.90%)低于对照组(35.48%),差异有统计学意义(P<0.05)。结论相对于平阳霉素,在口腔颌面-颈部脉管畸形患者中采用超声引导下的聚桂醇硬化治疗可提高治疗效果,可减少硬化剂使用量,减轻术后疼痛程度。还可以降低患者术后炎症水平,并提高患者对外观满意度。Objective To analyze the clinical effects of ultrasound-guided polidocanol sclerotherapy for vascular malformations in the oral and maxillofacial-cervical regions.Methods A total of 62 patients with oral and maxillofacial-cervical vascular malformations treated at Zhoukou Traditional Chinese Medicine Hospital from October 2021 to October 2023 were selected.Patients were randomly divided into a control group and an observation group,with 31 patients in each group.The control group received intervention treatment with bleomycin,while the observation group underwent intervention treatment with polidocanol.The number of treatment sessions,amount of sclerosant used,postoperative pain levels,aesthetic satisfaction,treatment efficacy,inflammatory factors,maximum diameter of the lesion cavity,and adverse reactions were compared between the two groups.Results After treatment,the maximum diameter of the lesion cavity,postoperative pain scores,and amount of sclerosant used in the observation group were significantly lower than those in the control group(P<0.05).The treatment efficacy rate in the observation group(93.55%)was higher than that in the control group(74.19%),and aesthetic satisfaction(90.32%)was also higher in the observation group compared to the control group(67.74%)with significant differences(P<0.05).The levels of inflammatory factors in the observation group were lower than those in the control group,showing statistically significant differences(P<0.05).The incidence of adverse reactions in the observation group(12.90%)was lower than that in the control group(35.48%),with significant differences(P<0.05).Conclusion Compared to bleomycin,ultrasound-guided polidocanol sclerotherapy is more effective in treating vascular malformations in the oral and maxillofacial-cervical regions.This method not only enhances treatment outcomes but also reduces the amount of sclerosant used,alleviates postoperative pain,lowers postoperative inflammation levels,and increases patient satisfaction with aesthetics.
关 键 词:口腔颌面-颈部脉管畸形 超声引导 介入治疗 聚桂醇硬化剂
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