Sensitive and selective electrochemical sensor for the detection of dopamine by using AuPd@Fe_(2)O_(3) nanoparticles as catalyst  

作　　者：Mengjiao Dai Qunyan Zhu Dongxue Han Li Niu Zhenxin Wang 

机构地区：[1]State Key Laboratory of Electroanalytical Chemistry,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022,China [2]University of Science and Technology of China,Hefei 230026,China [3]National Analytical Research Center of Electrochemistry and Spectroscopy,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022,China [4]Guangzhou Key Laboratory of Sensing Materials and Devices,Center for Advanced Analytical Science,School of Chemistry and Chemical Engineering,Guangzhou University,Guangzhou 510006,China [5]Guangdong Provincial Key Laboratory of Psychoactive Substances Monitoring and Safety,Anti-Drug Technology Center of Guangdong Province,Guangzhou 510230,China

出　　处：《Advanced Sensor and Energy Materials》2023年第1期24-31,共8页先进传感器与能源材料（英文）

基　　金：National Natural Science Foundation of China(Grant no.21974133).

摘　　要：The levels of dopamine(DA)in living organisms have strong effects on many biological processes and diseases,such as Parkinson's disease and Alzheimer's disease.Therefore,it has great significance for sensitive and selective detection of DA.Herein,the AuPd@Fe_(2)O_(3) nanoparticles-based electrochemical(EC)sensor(AuPd@Fe_(2)O_(3) NPs/GCE)is developed for chronoamperometric detection of DA with high sensitivity and good anti-interference ability through simple immobilization of AuPd@Fe_(2)O_(3) nanoparticles on glassy carbon electrode(GCE)by Nafion.Under the application of oxidation potential,the AuPd@Fe_(2)O_(3) NPs/GCE exhibits good electrocatalytic activity toward DA,which enables to linearly detect DA in the range of 10 nM–831.61μM(R^(2)=0.9983).The AuPd@Fe_(2)O_(3) NPs/GCE also shows good selectivity and reproducibility for the detection of DA.Furthermore,the practicability of AuPd@Fe_(2)O_(3) NPs/GCE has been demonstrated by detection of DA in dopamine hydrochloride injection and human serum.

关 键 词：Electrochemical sensor AuPd@Fe_(2)O_(3)nanoparticles DOPAMINE High sensitivity Good anti-interference ability 

分 类 号：O65[理学—分析化学]