基于CiteSpace的龋病微生态微生物领域的趋势与热点研究  

CiteSpace⁃based analysis of research trends and hotspots in the field of microbiomes and microbes of dental caries

作　　者：徐万宁 廖玍[2] 彭显 周学东[1] XU Wanning;LIAO Ga;PENG Xian;ZHOU Xuedong(State Key Laboratory of Oral Diseases&Nation-al Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Operative Dentistry and Endodontics,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China;State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China)

机构地区：[1]口腔疾病防治全国重点实验室、国家口腔医学中心、国家口腔疾病临床医学研究中心、四川大学华西口腔医院牙体牙髓病科,四川成都610041 [2]口腔疾病防治全国重点实验室、国家口腔医学中心、国家口腔疾病临床医学研究中心、四川大学华西口腔医院,四川成都610041

出　　处：《口腔疾病防治》2024年第12期933-944,共12页Journal of Prevention and Treatment for Stomatological Diseases

基　　金：国家自然科学基金面上项目(32371523)。

摘　　要：目的探究龋病微生态微生物领域相关研究的趋势与热点,为龋病研究提供参考。方法本研究从Web of Science核心合集(Web of Science Core Collection,WOSCC)数据库中提取了2014至2023年发表的龋病微生态微生物领域相关文献,通过CiteSpace文献计量学可视化评估方法对该研究领域的发文量、期刊、国家、作者、机构、共被引文献、关键词等方面开展可视化分析。结果共纳入3192篇文献,其中研究型论文2664篇、综述528篇,年发文量总体呈上升趋势。美国和中国的发文量位居前列,但在国际合作方面美国处于优势。发文量占比前10的期刊主要是牙科学期刊,其次是微生物学期刊。发文量位居前列的作者网络有以四川大学周学东为主的作者网络以及以马里兰大学巴尔的摩分校Xu Hockin H.K和Weir Michael D为主的作者网络。龋病微生态微生物研究的活跃点集中在微生物致龋毒力及相互作用、口腔微生物群系、龋病与系统性疾病的关系等。共被引频次较高的文章主要涉及龋病、口腔生物膜、口腔微生物群系、变异链球菌等主题。关键词研究显示了在过去十年中龋病、变异链球菌、细菌、牙菌斑和抗菌活性一直是研究重点;健康、口腔健康等关键词的数量呈上升趋势。最新出现的“gut microbiome/microbiota”提示口腔⁃肠道微生物组轴是该领域的研究前沿,研究人员的视野逐渐转向龋病与全身疾病间的联系。结论近10年关于龋病微生态微生物领域相关文献的发文量逐年上升,研究趋势将朝口腔微生物多组学方向发展,新的研究方法和技术将会促进龋病学研究领域的发展.Objective To analyze the trends and hotspots in research related to microbiomes and microbes of den⁃tal caries;in addition,the study seeks to provide a reference for caries research.Methods We searched the Web of Science Core Collection(WOSCC)to extract relevant literature in the field of microbiomes and microbes of dental caries published from 2014 to 2023.We used bibliometric visualization evaluation methods such as CiteSpace to conduct visu⁃alized analysis of factors that include the number of publications,journals,countries,authors,institutions,co⁃cited refer⁃ences,and keywords.Results A total of 3192 references were extracted,including 2664 articles and 528 reviews.The number of annual publications is increasing.The United States and China lead the number of publications,with the United States demonstrating a greater capacity for international collaboration.The top 10 journals in percentage of litera⁃ture are mainly in the field of dentistry followed by the field of microbiology.The author cooperation networks with the highest number of publications include the network led by Zhou Xuedong of Sichuan University,and the network led by Xu Hockin H.K and Weir Michael D of the University of Maryland,Baltimore.The research on microbiomes and mi⁃crobes of dental caries focuses on the cariogenic toxicity and interaction of microorganisms,oral microbiomes,and the relationship between dental caries and systemic diseases.The articles with high citation frequency mainly involve topics such as dental caries,oral biofilm,oral microbiota,and Streptococcus mutans.Keyword research showed that“dental car⁃ies,”“Streptococcus mutans,”“bacteria,”“dental plaque,”and“antibacterial activity”have been the primary focus of research in the last decade.The number of keywords,such as“health”and“oral health,”is on the rise.The latest emergence of“gut microbiome/microbiota”suggests that the oral gut microbiome axis is at the forefront of research in this field,and researchers’focus is gradua

关 键 词：龋病 口腔微生态 口腔微生物 生物膜 变异链球菌 口腔⁃肠道微生物组轴 口腔健康 文献计量学 可视化分析研究 研究趋势 口腔微生物多组学 

分 类 号：R78[医药卫生—口腔医学]