老年卵巢癌化疗致周围神经炎患者跌倒恐惧现状及影响因素分析  

Current status of fear of falling in elderly patients with chemotherapy induced peripheral neuropathy for ovarian cancer and its influencing fartors analysis

作　　者：张佳 袁菁 崔秀云 张宇婷 吴雅茹 徐春艳[2] ZHANG Jia;YUAN Jing;CUI Xiuyun;ZHANG Yuting;WU Yaru;XU Chunyan(School of Nursing,Xinjiang Medical University,Xinjiang Uygur Autonomous Region,Urumqi830011,China;the Third Department of Gynecological Surgery,Affiliated Tumor Hospital of Xinjiang Medical University,Xinjiang Uygur Autonomous Region,Urumqi830011,China)

机构地区：[1]新疆医科大学护理学院,新疆乌鲁木齐830011 [2]新疆医科大学附属肿瘤医院妇外三科,新疆乌鲁木齐830011

出　　处：《中国医药导报》2024年第26期191-196,共6页China Medical Herald

基　　金：新疆维吾尔自治区卫生健康委员会“天山英才”医药卫生高层次人才培养计划项目(TSYC202301B161)。

摘　　要：目的调查老年卵巢癌化疗致周围神经炎(CIPN)患者跌倒恐惧(FOF)的发生状况,探讨其相关影响因素,为制订精准护理方案提供参考依据。方法2023年8月至2024年5月,采用便利抽样法,选取新疆医科大学附属肿瘤医院妇科病区的234例老年卵巢癌CIPN患者为研究对象,使用一般资料调查表、癌症患者化疗导致周围神经病变评估量表(CAS-CIPN)及修订版跌倒恐惧量表(FFQ-R)进行问卷调查,采用多元线性回归分析相关影响因素。结果不同年龄、体重指数、化疗周期、睡眠质量、卵巢癌复发、近1年跌倒经历、有新辅助化疗史、锻炼的老年卵巢癌患者FFQ-R评分比较,差异有统计学意义(P<0.05)。老年卵巢癌患者CAS-CIPN评分为(22.61±7.30)分,FFQ-R评分为(38.46±3.41)分,患者CAS-CIPN评分与FFQ-R评分呈正相关(r=0.437,P<0.01)。多因素分析显示,睡眠质量、CAS-CIPN评分是老年卵巢癌CIPN患者FOF的影响因素(P<0.05)。结论老年卵巢癌CIPN患者FOF水平较高,建议医护人员应将FOF纳入老年卵巢癌患者症状管理中,针对高危因素制订个体化运动及心理护理干预,以提升患者的生存质量。Objective To investigate the occurrence status of fear of falling(FOF)in elderly ovarian cancer chemotherapy-induced peripheral neuritis(CIPN)patients,explore its related influencing factors,and provide a reference basis for the development of precise nursing programs.Methods From August 2023 to May 2024,234 elderly ovarian cancer CIPN patients in the Gynecology Ward of Affiliated Tumor Hospital of Xinjiang Medical University were selected by convenience sampling method,and questionnaires were administered,the general information questionnaire,the comprehensive assessment scale for chemotherapy-induced peripheral neuropathy in cancer(CAS-CIPN),and the fear of falling questionnaire-revised(FFQ-R)were used,multiplelinear regression was used to analyze the influencing factors of FOF.Results The FFQ-R scores of elderly ovarian cancer patients of different ages,body mass index,chemotherapy cycle,sleep quality,ovarian cancer recurrence,the experience of fall in the last year,history of neoadjuvant chemotherapy,and exercise were compared,and the differences were statistically significant(P<0.05).The CAS-CIPN score of elderly ovarian cancer patients was(22.61±7.30)points.The FFQ-R score was(38.46±3.41)points.Patients’CAS-CIPN scores were positively correlated with FFQ-R scores(r=0.437,P<0.01).Multifactorial analysis showed that sleep quality and CAS-CIPN score were influencing factors for FOF in elderly ovarian cancer CIPN patients(P<0.05).Conclusion Elderly ovarian cancer patients with CIPN have high levels of FOF,and it is recommended that healthcare professionals incorporate FOF into the symptom management of elderly ovarian cancer patients,and formulate individualized exercise and psychological care interventions for high-risk factors to enhance the quality of patients’survival.

关 键 词：卵巢癌 化疗致周围神经炎 跌倒恐惧 影响因素 

分 类 号：R737.31[医药卫生—肿瘤] R745[医药卫生—临床医学] R-055