抑郁症相关干眼症的研究进展  

Research progress on depression related xerophthalmia

作　　者：陈宝仪 郑振优 CHEN Baoyi;ZHENG Zhenyou(Department of Ophthalmology,the First Affiliated Hospital of Hainan Medical University,Hainan Province,Haikou570100,China)

机构地区：[1]海南医科大学第一附属医院眼科,海南海口570100

出　　处：《中国医药导报》2024年第30期74-78,共5页China Medical Herald

摘　　要：干眼症是一类慢性眼表疾病,因其较高的发病率成为眼科最常见的疾病之一,长期的眼部不适症状可对患者心理造成负面影响。抑郁症作为一种精神障碍,其特征包括心理状态异常及某些躯体化症状,近年来,越来越多研究显示抑郁症与干眼症可能存在密切关系。尽管目前两者共同致病机制尚不明确,但已有部分研究提供新的发现和研究方向。本文对这些研究成果进行综述,探讨抑郁症与干眼症的潜在机制和联系,分析抗抑郁药物对眼表的影响,并为治疗抑郁症相关干眼症提供更多思路和方法。Xerophthalmia is a chronic ocular surface disease,because of its high incidence rate,it has become one of the most common diseases in ophthalmology.Long term ocular discomfort may have a negative impact on the mood of patients.Depression,as a mental disorder,is characterized by abnormal psychological states and certain somatic symptoms.In recent years,an increasing number of studies have shown a close relationship between depression and xerophthalmia.Although the common pathogenic mechanism between the two is currently unclear,some studies have provided new discoveries and research directions.This article reviewes these research findings,explore the potential mechanisms and connections between depression and xerophthalmia,analyze the effects of antidepressant drugs on the ocular surface,and provide more ideas and methods for treating depression related xerophthalmia.

关 键 词：干眼症 抑郁症 抗抑郁治疗 发病机制 诊断 

分 类 号：R777[医药卫生—眼科]