药物结合心理疗法在脑卒中后睡眠障碍患者中的应用效果分析  

Effect analysis of drug combined with psychotherapy in patients with post-stroke sleep disorders

作　　者：张玉龙 ZHANG Yu-long(Department of Neurology,East University Hospital of Pizhou,Pizhou 221300,China)

机构地区：[1]邳州东大医院神经内科,221300

出　　处：《中国现代药物应用》2024年第22期133-136,共4页Chinese Journal of Modern Drug Application

摘　　要：目的 分析药物结合心理疗法在脑卒中后睡眠障碍患者中的应用效果。方法 选择70例脑卒中后睡眠障碍患者,根据单双数法进行分组,单数分到观察组(n=35),双数分到对照组(n=35)。对照组行常规药物治疗,观察组行药物结合心理疗法。对比两组治疗前后睡眠质量[匹兹堡睡眠质量指数量表(PSQI)评分]、睡眠进程[睡眠潜伏期(SL)、总睡眠时间(TST)、觉醒次数(AT)]及睡眠结构[眼球快速运动睡眠时间(REM)、非眼球快速运动睡眠时间(NREM)]。结果 治疗后,观察组PSQI评分(6.45±0.56)分较对照组的(11.30±2.29)分更低(P<0.05)。治疗后,观察组SL(25.69±7.59)min、AT(4.60±1.07)次短/少于对照组的(41.02±10.06)min、(5.92±1.28)次,TST(360.18±29.98)min较对照组的(309.82±37.86)min更长(P<0.05)。治疗后,观察组REM(114.65±23.20)min及NREM的S2(132.18±27.98)min、S3+S4(31.82±7.29)min较对照组的(95.90±23.09)、(109.82±18.86)、(17.95±5.32)min更长(P<0.05)。结论 脑卒中后睡眠障碍应用药物结合心理疗法,可显著提高患者的睡眠质量,促进睡眠进程与结构的改善,值得推广应用。Objective To analyze the practical effect of drug combined with psychotherapy in patients with post-stroke sleep disorders.Methods A total of 70 patients with post-stroke sleep disorders were divided into the observation group(n=35 cases,odd number) and the control group(n=35 cases,even number) according to odd-even number method.The control group received conventional drug treatment,and the observation group received drug combined psychotherapy.Both groups were compared in terms of sleep quality [Pittsburgh sleep quality index(PSQI) score],sleep progress [sleep latency(SL),total sleep time(TST),awake times(AT)] and sleep structure [rapid eye movement(REM),non-rapid eye movement(NREM)] before and after treatment.Results After treatment,PSQI score of(6.45±0.56) points in the observation group was lower than(11.30±2.29) points in the control group(P<0.05).After treatment,the observation group had SL of(25.69±7.59) min and AT of(4.60±1.07) times,which were shorter/less than(41.02±10.06) min and(5.92±1.28) times in the control group;TST of(360.18±29.98) min in the observation group was longer than(309.82±37.86) min in the control group(P<0.05).After treatment,the observation group had REM of(114.65±23.20) min and NREM stage S2 of(132.18±27.98) min,and NREM stage S3 + S4 of(31.82±7.29) min,which were longer than(95.90±23.09),(109.82±18.86) and(17.95±5.32) min in the control group(P<0.05).Conclusion The application of drug combined with psychotherapy can significantly improve the sleep quality of patients with post-stroke sleep disorders,and promote the improvement of sleep process and structure,which is worthy of popularization and application.

关 键 词：药物 心理疗法 脑卒中 睡眠障碍 应用效果 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R740[医药卫生—临床医学]