彩色多普勒超声与血清肿瘤标志物联合检测在乳腺癌早期诊断中的应用价值分析  

Application Value Analysis of Color Doppler Ultrasonography Combined with Serum Tumor Markers in Early Diagnosis of Breast Cancer

作　　者：韩美兰 张伟锋 Han Meilan(Fuqing Hospital,Fuqing Fujian 350300)

机构地区：[1]福建省福清市医院,福建福清350300 [2]汕头大学,广东汕头515000

出　　处：《黑龙江医药》2024年第6期1241-1244,共4页Heilongjiang Medicine journal

基　　金：广东省自然科学基金项目(项目编号:2020A151501857)。

摘　　要：目的:探讨影像学方法联合肿瘤标志物检查方案对乳腺癌早期诊断的价值,以期提升临床鉴别准确性,帮助后续治疗方案的开展。方法:90例疑似乳腺癌患者入院后均分别进行彩色多普勒超声与血清肿瘤标志物检测,以手术病理结果为标准,分析两种检查方法单独检测与联合检测诊断乳腺癌的价值。结果:Kappa检验分析结果显示,彩色多普勒超声、血清肿瘤标志物诊断结果与手术病理结果一致性较为一般(Kappa值=0.783,0.766;P<0.05);联合检查方法对乳腺癌的诊断结果与临床筛查结果具有较高的一致性(Kappa值=0.940,P<0.05)。两种检查方法联合应用诊断乳腺癌的效能数据较单独检测结果明显更高(P<0.05)。结论:影像学方法与实验室指标相联合的检查方法在乳腺癌诊断中的应用更好,可为乳腺癌的临床诊断提供更为准确的数据参考,为后续治疗方案的及早制定与实施均具有指导意义,推荐推广应用。Objective:To explore the value of imaging methods combined with tumor marker examination program in the early diagnosis of breast cancer,in order to improve the accuracy of clinical differentiation and help the development of follow-up treatment programs.Methods:After admission,90 patients with suspected breast cancer were detected by color Doppler ultrasound and serum tumor markers respectively.The value of single detection and combined detection of the two methods was analyzed according to the pathological results of operation.Results:The results of Kappa test showed that the diagnostic results of color Doppler ultrasound and serum tumor markers were generally consistent with surgical pathological results(Kappa value=0.783,0.766;P<0.05);There was a high consistency between the diagnosis results of breast cancer and the clinical screening results(Kappa=0.940,P<0.05).The efficacy of the combined application of the two methods in the diagnosis of breast cancer was significantly higher than that of the single detection(P<0.05).Conclusion:The examination method combined with imaging method and laboratory index has better application in the diagnosis of breast cancer,which can provide more accurate data reference for the clinical diagnosis of breast cancer,and has guiding significance for the early formulation and implementation of follow-up treatment plan,and it is recommended to be popularized and applied.

关 键 词：彩色多普勒超声 血清肿瘤标志物 联合检测 乳腺癌 早期诊断 

分 类 号：R737.9[医药卫生—肿瘤]