Barriers to the Acceptance of Tuberculosis Preventive Treatment:A Multicenter Cross-sectional Study in China  

作　　者：Jingjuan Ren &Fei Huang Haifeng Chen Huimin Zhang Jianwei Sun Ahui Zhao Zuhui Xu Liqin Liu Huizhong Wu Lanjun Fang Chengguo Wu Qingya Wang Wenqian Zhang Xinhua Sun Xiaoping Liu Jizheng Yuan Bohan Chen Ni Wang Yanlin Zhao 

机构地区：[1]National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases,Chinese Center for Disease Control and Prevention,Beijing 102206,China [2]National Center for Tuberculosis Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China [3]Hebei Province Center for Disease Prevention and Control,Hebei 050021,China [4]Institute of Tuberculosis Control and Prevention,Henan Center for Disease Control and Prevention,Henan 450016,China [5]Hunan Institute for Tuberculosis Control(Hunan Chest Hospital),Hunan 410006,China [6]Center for Tuberculosis Control of Guangdong Province,Guangdong 510630,China [7]Chongqing Institute for Tuberculosis Prevention and Control,Chongqing 404100,China [8]Tianjin Center for Tuberculosis Control,Tianjin 300041,China [9]Chinese Foundation for Prevention of STD and AIDS,Beijing 100069,China [10]National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases,National Institute for Communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China

出　　处：《Biomedical and Environmental Sciences》2024年第11期1303-1309,共7页生物医学与环境科学（英文版）

基　　金：Public-Benefit Project on Tuberculosis Patient Care Action[09107].

摘　　要：Objective We aimed to understand the willingness and barriers to the acceptance of tuberculosis(TB)preventive treatment(TPT)among people with latent TB infection(LTBI)in China.Methods A multicenter cross-sectional study was conducted from May 18,2023 to December 31,2023 across 10 counties in China.According to a national technical guide,we included healthcare workers,students,teachers,and others occupations aged 15-65 years as our research participants.Results Overall,17.0%(183/1,077)of participants accepted TPT.There were statistically significant differences in the acceptance rate of TPT among different sexes,ages,educational levels,and occupations(P<0.05).The main barriers to TPT acceptance were misconceptions that it had uncertain effects on prevention(57.8%,517/894),and concerns about side effects(32.7%,292/894).Conclusion An enhanced and comprehensive understanding of LTBI and TPT among people with LTBI is vital to further expand TPT in China.Moreover,targeted policies need to be developed to address barriers faced by different groups of people.

关 键 词：Latent tuberculosis infection Tuberculosis preventive treatment ACCEPTANCE Healthcare workers STUDENTS TEACHERS 

分 类 号：R52[医药卫生—内科学]