市售牙膏中标签标识情况和风险物质的检测结果调查分析  

Investigation and Analysis of the Labels and Determination Results of the Risk Substances in Toothpaste on the Market

作　　者：熊雯 刘剑 吉伟佳 吴珍 龚玮 易路遥 Xiong Wen;Liu Jian;Ji Weijia;Wu Zhen;Gong Wei;Yi Luyao(Jiangxi Institute for Drug Control,NMPA Key Laboratory of Quality Evaluation of Traditional Chinese Patent Medicine,Jiangxi Province Engineering Research Center of Drug and Medical Device Quality,Nanchang Jiangxi 330029,China)

机构地区：[1]江西省药品检验检测研究院国家药品监督管理局中成药质量评价重点实验室江西省药品与医疗器械质量工程技术研究中心,江西南昌330029

出　　处：《实验与分析》2024年第4期78-82,共5页LABOR PRAXIS

基　　金：江西省药品监督管理局科技计划(2021KY50)。

摘　　要：通过对小型超市儿童牙膏标签标识情况进行跟踪统计,发现《牙膏监督管理办法》实施后,标签标识出现禁用字样和图案情况明显好转。为了解市售牙膏中风险物质的添加状况,通过网店、批发市场、小商店、超市等渠道采集101份样品,网络平台购入3批次消字号和1批次械备号非牙膏产品,另97批次牙膏采用经方法学验证的自建方法,对样品中7种人工甜味剂和3种止血药进行检测分析。结果表明:牙膏样品检出3种人工甜味剂糖精钠、三氯蔗糖和安赛蜜,检出率分别为88.66%、10.31%和1.03%;检出1种止血药氨甲环酸,检出率为6.19%;这些风险物质检出量较低;发现8批次检验结果与标签标识成分不一致产品。The banned words and patterns in the labels of children’s toothpaste were tracked and counted in small and medium-sized supermarkets,and it was found that the phenomenon of labels suggesting or misleading consumers has significantly improved after the implementation of the“Measures”.To analyze the current situation of addition of the risk substance and label information about packaging in toothpaste on the market,101 samples were collected from online shop,wholesale markets,small shops and supermarkets.When sampling online shopping,3 batches of disinfection products and 1 batch of medical device product were purchased,they were not toothpaste.Then according to methodologically validated self-built methods 97 toothpaste samples were detected for the determination of seven artificial sweeteners and three hemostatic agents.Three artificial sweeteners were detected including saccharin sodium,sucralose and acesulfame-K,the detection rates were 88.66%,10.31%and 1.03%,respectively.Tranexamic acid was detected,and the detection rate was 6.19%.The amount of these risk substances detected was low.A total of 8 batches products were found to have inconsistent label ingredients.

关 键 词：牙膏 人工甜味剂 止血药 标签标识成分不一致 

分 类 号：TQ658[化学工程—精细化工]