气滞胃痛颗粒联合常规西药治疗肝郁气滞型肠易激综合征患者的效果  

Effects of Qizhi Weitong granules combined with conventional Western medicine in treatment of patients with irritable bowel syndrome of liver qi stagnation type

作　　者：杨志伟 YANG Zhiwei(Department of Internal Medicine of Zhangpu County Second Hospital,Zhangzhou 363208 Fujian,China)

机构地区：[1]漳浦县第二医院内科,福建漳州363208

出　　处：《中国民康医学》2024年第23期84-86,90,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:观察气滞胃痛颗粒联合常规西药治疗肝郁气滞型肠易激综合征患者的效果。方法:选取2020年1月至2023年10月该院收治的80例肝郁气滞型肠易激综合征患者进行前瞻性研究,通过随机数字表法将其分为对照组和观察组各40例。对照组采用常规西药治疗,观察组在对照组基础上采用气滞胃痛颗粒治疗,比较两组临床疗效,治疗前后中医证候积分、炎性指标[白细胞计数(WBC)、C反应蛋白(CRP)]水平、病情严重程度[肠易激综合征病情程度量表(IBS-SSS)]评分、生命质量[肠易激综合征-生命质量测量量表(IBS-QOL)]评分,以及不良反应发生率。结果:观察组治疗总有效率为95.00%(38/40),高于对照组的75.00%(30/40),差异有统计学意义(P<0.05);治疗后,观察组中医证候积分低于对照组,差异有统计学意义(P<0.05);治疗后,观察组CRP、WBC水平均低于对照组,差异有统计学意义(P<0.05);治疗后,观察组IBS-SSS和IBS-QOL评分均低于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:在常规西药治疗基础上采用气滞胃痛颗粒治疗肝郁气滞型肠易激综合征患者可提高治疗总有效率,降低中医证候积分、炎性指标水平、IBS-SSS评分和IBS-QOL评分,效果优于单纯常规西药治疗。Objective:To observe effects of Qizhi Weitong granules combined with conventional Western medicine in treatment of patients with irritable bowel syndrome of liver qi stagnation type.Methods:A prospective study was conducted on 80 patients with irritable bowel syndrome of liver qi stagnation type admitted to this hospital from January 2020 to October 2023.They were divided into control group and observation group by using the random number table method,40 cases in each group.The control group was treated with conventional Western medicine,while the observation group was treated with Qizhi Weitong granules on the basis of that of the control group.The clinical efficacy,the TCM syndrome score,the inflammatory index[white blood cell count(WBC),C-reactive protein(CRP)]levels,the severity of disease[irritable bowel syndrome severity scale(IBS-SSS)]score and the quality of life[irritable bowel syndrome-quality of life scale(IBS-QOL)]score before and after the treatment,and incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was 95.00%(38/40),which was higher than 75.00%(30/40)of the control group,and the difference was statistically significant(P<0.05).After the treatment,the TCM syndrome score of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).After the treatment,the levels of CRP and WBC in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the scores of IBS-SSS and IBS-QOL in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:On the basis of conventional Western medicine treatment,Qizhi Weitong granules can improve the total effective rate of treatment and reduce the TCM syndrome scores,t

关 键 词：气滞胃痛颗粒 肝郁气滞型 肠易激综合征 中医证候积分 炎性指标 生命质量 

分 类 号：R574[医药卫生—消化系统]