自体角膜缘干细胞移植术与羊膜移植术治疗翼状胬肉的临床效果比较  

Comparison of Clinical Effects of Current Limbal Stem Transplantation Techniquesand Amniotic Membrane Transplantation in the Treatment of Pterygium

作　　者：程小燕 CHENG Xiaoyan(Quannan County People's Hospital,Quannan 341800,Jiangxi,China)

机构地区：[1]全南县人民医院,江西全南341800

出　　处：《现代诊断与治疗》2024年第14期2055-2057,共3页Modern Diagnosis and Treatment

摘　　要：目的比较自体角膜缘干细胞移植术(CAT)与羊膜移植术翼状胬肉的临床效果。方法选取2020年1月至2023年6月我院收治的60例翼状胬肉患者为研究对象,采用随机数字表法分为研究组和对照组各30例,两组均行改良式翼状胬肉切除术,对照组采用羊膜移植术,研究组采用CAT术。对比两组视力质量、泪膜功能、并发症及复发情况。结果术后,两组角膜水平曲度、角膜垂直曲度、视力均高于术前(P<0.05),角膜散光度均低于术前(P<0.05),研究组视力质量高于对照组(P<0.05);术后,两组BUT、SⅠT均高于术前(P<0.05),且研究组高于对照组(P<0.05);研究组并发症发生率低于对照组(P<0.05);研究组复发率低于对照组(P<0.05)。结论改善式翼状胬肉切除术中采用CAT术治疗,能够提高患者视力质量,缓解泪膜功能,减少并发症和复发情况,效果优于羊膜移植术。Objectives To compare the clinical efficacy of current limbal stem transplantation techniques(CAT)and amniotic membrane transplantation in the treatment of pterygium.Methods A total of 60 patients with pterygium from January 2020 to June 2023 who were admitted to our hospital wereselected and randomly divided into study group and observation group,with 30 cases in each group.Both groups underwent modified pterygium excision,and the control group received amniotic membrane transplantation while the study group underwent CAT surgery.The visual quality,tear film function,complications and recurrence were compared between the two groups.Results After surgery,the corneal horizontal curvature and vertical curvature of the two groups were significantly higher than those before operation(P<0.05),and the corneal astigmatism was significantly lowered.The visual quality of the study group was significantly higher than that in the control group(P<0.05).After surgery,BUT and SIT in both groups were significantly improved(P<0.05),and those in the study group were significantly higher than those in control group(P<0.05).The incidence of complications in the study group was significantly lower than that in the control group(P<0.05),and the recurrence rate of the study group was significantly lowerthan that of the control group(P<0.05).Conclusions The application of CAT surgery in modified pterygium excision can improve the visual quality of patients,alleviate tear film function,reduce complications and recurrence,and the effect is better than amniotic membrane transplantation.

关 键 词：改良式翼状胬肉切除术 自体角膜缘干细胞移植术 羊膜移植术 翼状胬肉 

分 类 号：R779.6[医药卫生—眼科]