儿童急性淋巴细胞白血病复发机制研究进展  

Research Progress on Recurrence Mechanism of Childhood Acute Lymphoblastic Leukemia

作　　者：张婷 姚秀云 ZHANG Ting;YAO Xiuyun(Department of Hematology,Tianjin Children’s Hospital,Tianjin 300134,China)

机构地区：[1]天津市儿童医院,天津300134

出　　处：《现代诊断与治疗》2024年第15期2259-2260,2263,共3页Modern Diagnosis and Treatment

摘　　要：儿童急性淋巴细胞白血病(ALL)是从淋巴B、T细胞起源,并在骨髓内异常增生的一种恶性血液系统疾病。化疗是治疗该病的主要手段,有着较高的治愈率,但治疗后很多患儿的病情依然会复发,且目前对于其具体复发机制还未完全清楚。希望通过开展大样本数据研究及大样本疾病队列随访来明确其复发机制,据此进行个体化治疗,进而推动儿童ALL临床诊治技术的发展及进步。Childhood Acute Lymphoblastic Leukemia(ALL)is a malignant hematological disease that originates from lymphoid B and T cells and proliferates abnormally in the bone marrow.Chemotherapy is the main method forthe treatmentof the disease,with a high cure rate.However,many children still relapse after treatment,and the specific recurrence mechanism has not beenfully understoodso far.We hope to clarify the mechanism of relapse by conducting large sample data research and large sample disease cohort follow-up,so as to carry out individualized treatment and promote the development and progress of clinical diagnosis and treatment technology for childhood ALL.

关 键 词：儿童 急性淋巴细胞白血病 复发机制 研究进展 

分 类 号：R733.7[医药卫生—肿瘤]