含马齿苋发酵提取物的乳霜功效研究  

Study on the Efficacy of Cream Containing Fermented Portulaca Oleracea L.Extract

作　　者：许显 喻明英 赵文俊 杜冰[1] Xu Xian;Yu Mingying;Zhao Wenjun;Du Bing(South China Agricultural University,Guangzhou 510642,China;Huaan Tang Biotech Group Co.,Ltd.,Guangzhou 511434,China)

机构地区：[1]华南农业大学,广东广州510642 [2]花安堂生物科技集团有限公司,广东广州511434

出　　处：《广东化工》2024年第23期57-59,69,共4页Guangdong Chemical Industry

摘　　要：以马齿苋提取物、马齿苋发酵提取物为主要有效成分,分别配制了A、B两款乳霜并进行人体临床功效对比。测试受试者使用前后第0周、第1周、第2周和第4周的皮肤角质层含水量、经皮水分流失TEWL值和皮肤红斑指数EI值,并使用VISIA 7面部图像分析仪拍摄受试者面部图片,分析受试者测试前后的皮肤红度a*值、VISIA红区特征计数。结果显示,使用A、B两组乳霜样品之后,受试者的测试区域角质层含水量、经皮水分流失TEWL值、皮肤红斑指数EI值和皮肤红度a*值均有显著性改善(P<0.001),且添加马齿苋发酵提取物的B组相较于A组在使用4周后表现出更优的皮肤红斑指数改善效果(P<0.05)。而在VISIA红区特征计数的表现上,添加马齿苋发酵提取物的B组在使用1周、2周和4周后的变化率分别为13.76%(P<0.01),9.60%(P<0.05)和12.85%(P<0.001),添加马齿苋提取物的A组则无显著性(P>0.05)。本研究中的马齿苋发酵提取物相较于未发酵的马齿苋提取物具有更优的舒缓和褪红功效。With fermented Portulaca Oleracea L.(PO)extract and PO extract as the main active ingredients,two creams A and B were prepared respectively,and the human clinic efficacy was compared.The water content of the stratum corneum,the TEWL value and the EI value of the skin erythema index were measuredat week 0,week 1,week 2 and week 4,and the facial pictures of the subjects were taken via the VISIA 7 skin analysis apparatus,the skin redness a*value and VISIAred zone feature count before and after the test were analyzed.The results showed that after using the cream samples A and B,the water content of the stratumcorneum,the TEWL,the EI value of the skin erythema index and the a*value of skin redness in the test area were significantly improved(P<0.001),and the groupB with fermented PO extract showed better improvement on the skin erythema index after 4 weeks of application than group A(P<0.05).In terms of the VISIA redzone feature count,the change rates of group B after 1 week,2 weeks and 4 weeks of application were 13.76%(P<0.01),9.60%(P<0.05)and 12.85%(P<0.001),respectively,while the group A with PO extract was not significant(P>0.05).The fermented PO extract in this study had superior soothing and fadingredness effects compared to the unfermented PO.

关 键 词：马齿苋 发酵 泛红 舒缓 

分 类 号：TQ[化学工程]