固相萃取-气相色谱串联质谱法测定生活饮用水中8种亚硝胺类化合物  

Determination of Nitrosamines in Drinking Water by Solid Phase Extraction Gas Chromatography/Tandem Mass Spectrometry

作　　者：张祥汉 冯冬雪 钟建军 冯秋仪 秦伟 Zhang Xianghan;Feng Dongxue;Zhong Jianjun;Feng Qiuyi;Qin Wei(Zhuhai Water Supply and Drainage Pollution Control Center,Zhuhai 519000,China;Guangdong Shipu Testing Service Co.,Ltd.,Guangzhou 510000,China)

机构地区：[1]珠海市供水与排水治污中心,广东珠海519000 [2]广东实朴检测服务有限公司,广东广州510000

出　　处：《广东化工》2024年第21期146-148,共3页Guangdong Chemical Industry

摘　　要：近年来,含氮消毒副产物由于高遗传病毒性而被人们广泛认识,典型N-DBPs卤乙腈和亚硝胺类(NAs)已经被多个国家或组织纳入饮用水水质标准。为准确检测生活饮用水中的亚硝胺类化合物,本研究采用固相萃取法处理生活饮用水,用气相色谱-串联质谱仪测定生活饮用水中8种亚硝胺类化合物,通过优化固相萃取条件及气质联用仪的分析测定条件,使方法在25μg/L~625μg/L范围内线性良好。检出限和定量限分别为1.44 ng/L~4.20 ng/L,空白水样未检出,水样加标回收率为81.3%~114%,方法的精密度和准确度良好。此优化方法适用于生活饮用水中8种常见亚硝胺类化合物的检测。In recent years,nitrogen containing disinfection by-products have been widely recognized due to their high genetic and viral properties.Typical N-DBPs haloacetonitrile and nitrosamines(NAs) have been included in drinking water quality standards by multiple countries or organizations.In order to accurately detect nitrosamine compounds in drinking water,this study used solid-phase extraction to treat drinking water and determined 8 nitrosamine compounds in drinking water using gas chromatography-tandem mass spectrometry.By optimizing the solid-phase extraction conditions and the analysis and determination conditions of the gas chromatography-mass spectrometer,the method was optimized good linearity within the range of 25 μg/L~625 μg/L.The detection limit and quantification limit are 1.44 ng/L~4.20 ng/L,respectively.The blank water sample was not detected,and the recovery rate of water sample spiking was 81.3 %~114 %.The precision and accuracy of the method are good.This optimization method is applicable for the detection of 8 common nitrosamine compounds in drinking water.

关 键 词：亚硝胺类 固相萃取 气相色谱-串联质谱法 生活饮用水 

分 类 号：TQ[化学工程]