长期住院精神分裂症患者合并不同躯体疾患的发生率及影响因素研究  

Study on the incidence and influencing factors of different physical disorders in long-term hospitalized patients with schizophrenia

作　　者：张海霞 俞燕华 ZHANG Haixia;YU Yanhua(Department of Psychiatry,Mental Health Center of Minhang District,Shanghai 201112,China)

机构地区：[1]上海市闵行区精神卫生中心精神科,上海201112

出　　处：《检验医学与临床》2024年第S02期154-157,共4页Laboratory Medicine and Clinic

摘　　要：目的调查分析精神分裂症患者合并不同躯体疾患的发病率以及各项临床指标,探讨其影响因素,提高专科医生识别精神分裂症患者合并躯体疾患征的风险意识。方法选取2022年1月-2023年1月于该院接受长期住院治疗的60例精神分裂症合并躯体症状患者为研究组,以非躯体症状患者为对照组,共60例(病例配比为1∶1),统计患者一般资料及合并发生躯体疾病的情况,并分析影响躯体疾病的相关因素。结果经单因素分析结果显示:(1)研究组患者年龄≥50岁比例66.67%高于对照组43.33%,差异有统计学意义(χ^(2)=6.599,P<0.05);(2)病程分布方面,研究组病程≥5年患者比例75.00%显著高于对照组55.00%,差异有统计学意义(χ^(2)=5.275,P<0.05);(3)既往居住特征方面,研究组有流浪史患者比例81.67%显著高于对照组58.33%,差异有统计学意义(χ^(2)=7.778,P<0.05);(4)服药时间方面,研究组≥5年患者比例46.67%明显高于对照组25.00%,差异有统计学意义(χ^(2)=6.125,P<0.05);经logistic回归进一步证实,年龄、病程、流浪史及服药时间是躯体和疾病的影响因素。结论长期住院的精神分裂症患者的躯体疾病类型多样,普遍存在。患者的年龄、流浪史、病程及服药时间均会影响躯体疾病的发生,说明有必要进行多个方向的诊断,加强重视并积极进行有效防治,符合治疗原则。Objective To investigate and analyze the incidence rate and clinical indicators of schizophrenia patients with different physical disorders,explore the influencing factors,and improve the risk awareness of specialists in identifying schizophrenia patients with physical disorders.Methods A total of 60 patients with schizophrenia and physical symptoms who received long-term hospitalized treatment from January 2022 to January 2023 were selected as a research group,and non physical symptom patients were selected as a control group,with a total of 60 cases(case ratio of 1∶1).The general information of patients and the incidence of physical diseases were collected,and the related factors affecting physical diseases were analyzed.Results The single factor analysis showed that,(1)the proportion of patients aged≥50 in the research group was 66.67%higher than the control group,which was 43.33%,and the difference was statistically significant(χ^(2)=6.599,P<0.05);(2)In terms of disease course distribution,the proportion of patients with a disease course of≥5 years in the research group(75.00%)was significantly higher than the control group(55.00%),and the difference was statistically significant(χ^(2)=5.275,P<0.05);(3)In terms of previous residential characteristics,the proportion of patients with wandering history in the research group was 81.67%,which was significantly higher than the control group(58.33%),and the difference was statistically significant(χ^(2)=7.778,P<0.05);(4)In terms of medication duration,46.67%of patients in the research group who had been taking medication for≥5 years were significantly higher than 25.00%in the control group,and the difference was statistically significant(χ^(2)=6.125,P<0.05);Further logistic regression confirmed that age,disease duration,wandering history,and medication duration were influenced factors for physical and disease outcomes.Conclusion The physical diseases diverse of schizophrenia patients in long-term hospitalized,and ubiquitous.The age,wandering history,dise

关 键 词：长期住院 精神分裂症 躯体疾患 

分 类 号：R749.3[医药卫生—神经病学与精神病学]