影响前列腺根治性切除术后Gleason评分升级的相关预测因素  

Predictive factors associated with Gleason score upgrading after radical prostatectomy

作　　者：陈治钦 陈鑫阳 李煜 殷虎明 谢赣生[1] 李纲[1] CHEN Zhiqin;CHEN Xinyang;LI Yu;YIN Huming;XIE Gansheng;LI Gang(Department of Urology,First Affiliated Hospital of Soochow University,Suzhou,Jiangsu,215031,China)

机构地区：[1]苏州大学附属第一医院泌尿外科,江苏苏州215031

出　　处：《临床泌尿外科杂志》2024年第11期1023-1030,共8页Journal of Clinical Urology

摘　　要：Gleason评分作为一种被广泛使用的前列腺癌分级系统,其准确评分是制定前列腺癌治疗方案的重要步骤。尽管目前穿刺活检技术在不断进步,但前列腺根治性切除术后的Gleason评分升级仍然很常见。Gleason评分升级使临床医生术前低估了肿瘤的危险度,可能导致治疗不足,影响预后。本文回顾了近6年的相关文献,并对前列腺根治性切除术后的Gleason评分升级相关预测因素的研究进展进行综述,旨在帮助临床医生在前列腺癌的诊疗过程中做出精确的病情评估和有利于改善患者预后的治疗决策。Gleason score is a widely used grading system for prostate cancer. Its precise determination is one of the most important initial steps in the management of prostate cancer. Despite current advances in puncture biopsy techniques, Gleason score upgrading after radical prostatectomy remains common. Gleason score upgrading causes clinicians to underestimate the risk of the tumor preoperatively, which might lead to inadequate treatments and a poorer prognosis. In this article, we review the relevant literature in the last six years and summarize the research progress in the predictive factors related to Gleason score upgrading after radical prostatectomy, aiming to help clinicians to make accurate assessment of the disease and treatment decisions conducive to the improvement of patient's prognosis during the management of prostate cancer.

关 键 词：前列腺癌 GLEASON评分 预测因素 

分 类 号：R737.25[医药卫生—肿瘤]