左足颗粒细胞瘤一例  

Granulosa cell tumor on the left heel:a case report

作　　者：张雪燕 张铭凯 曹楠[1,2] 陈声利 ZHANG Xueyan;ZHANG Mingkai;CAO Nan;CHEN Shengli(Hospital for Skin Diseases,Shandong First Medical University,Jinan 250022,China;Shandong Provincial Institute of Dermatology and Venereology,Shandong Academy of Medical Sciences,Jinan 250022,China)

机构地区：[1]山东第一医科大学附属皮肤病医院,山东济南250022 [2]山东省皮肤病性病防治研究所,山东济南250022

出　　处：《中国麻风皮肤病杂志》2025年第1期64-65,共2页China Journal of Leprosy and Skin Diseases

基　　金：山东省皮肤性病学临床医学研究中心。

摘　　要：颗粒细胞瘤(granular cell tumor,GCT)是一种罕见软组织肿瘤,临床皮损不典型,好发于头颈部,发生于足部者少见。本患者左足跟角质性斑块20年,组织病理示:真皮内见大圆形细胞排列成巢状,细胞核小、居中,胞质内见嗜酸性颗粒。免疫组化:S-100(+)、SOX10(+)、NSE(+)、CD68(+)。诊断为颗粒细胞瘤,予以手术切除。Granular cell tumor(GCT)is a rare soft tissue tumor.The skin lesions are atypical and usually occur in the head and neck,but rarely on the feet.The patient presented with keratinous plaques on the left heel for 20 years.Histopathology showed large circular cells arranged in nests within the dermis,the nucleus is small and centered,acidophilic granules can be seen in the cytoplasm.Immunohistochemistry showed S-100(+),SOX10(+),NSE(+),CD68(+).The patient was diagnosed with granulosa cell tumor and underwent surgical resection.

关 键 词：左足跟 颗粒细胞瘤 诊断 

分 类 号：R738.6[医药卫生—肿瘤]