侵入性神经电刺激治疗癫痫的应用及伦理考虑  

Ethical Consideration and Application of Invasive Nerve Electrical Stimulation in Treating Epilepsy

作　　者：杨毅 王凡 刘卓[2] YANG Yi;WANG Fan;LIU Zhuo(Department of Science Research Management,Taihe County People’s Hospital,Fuyang Anhui 236600,China;School of Engineering Medicine,Beihang University,Beijing 100191,China)

机构地区：[1]太和县人民医院科研管理科,安徽阜阳236600 [2]北京航空航天大学医学科学与工程学院,北京100191

出　　处：《中国医疗设备》2024年第12期131-135,共5页China Medical Devices

基　　金：国家自然科学基金(82372141)。

摘　　要：神经电刺激技术包括迷走神经电刺激术、反应性神经电刺激术、脑深部电刺激术,是针对耐药性癫痫和不适用传统癫痫手术患者的有效治疗方法。随着近年来神经电刺激技术的不断发展完善,其在治疗耐药性癫痫的适用范围逐渐扩大。在临床应用中,除了考虑患者个体的适应证外,还需考虑应用过程中潜在的伦理问题,如患者自主性、风险受益比、患者期望过高、隐私安全等,以充分保护患者权益,促进医疗新技术临床应用的规范化与安全性。本文旨在探讨神经电刺激治疗技术在临床应用过程中出现的或潜在的医学伦理问题,以进一步规范其在临床上的研究和应用。Nerve electrical stimulation techniques,including vagus nerve stimulation,responsive neurostimulation,and deep brain stimulation,are effective treatment methods for patients with drug-resistant epilepsy and those unsuitable for traditional epilepsy surgery.With the continuous progress and improvement of nerve electrical stimulation techniques in recent years,their application in treating drug-resistant epilepsy has gradually expanded.In clinical practice,in addition to considering the individual indications for patients,potential ethical issues during the application process need to be considered,such as patient autonomy,risk-benefit ratio,patient unrealistic expectations and privacy security,to fully protect patients’rights and promote the standardization and safety of the clinical application of new medical technologies.This article reviewed the medical ethical issues that might arise or potentially arise during the clinical application of nerve electrical stimulation therapy technology,in order to further standardize its research and application in clinical practice.

关 键 词：神经电刺激 癫痫 慢性脑部疾病 认知障碍 医学伦理 

分 类 号：R743.3[医药卫生—神经病学与精神病学]