中草药与针刺疗法调控多巴胺系统干预儿童抽动障碍的机制研究进展  

Research progress on the mechanism of Chinese herbal medicine and acupuncture therapy in regulating dopamine system for intervention in childhood tic disorders

作　　者：刘丽[1] LIU Li(Department of Traditional Chinese Medicine,Jiaxing Women and Children's Health Hospital,Jiaxing,Zhejiang,314001,China)

机构地区：[1]嘉兴市妇幼保健院中医科,浙江嘉兴314001

出　　处：《中医儿科杂志》2024年第6期103-107,共5页Journal of Pediatrics of Traditional Chinese Medicine

摘　　要：中草药与针刺疗法干预儿童抽动障碍的效应机制研究取得了进展,如何有效调控多巴胺(DA)系统使得DA的效应浓度得以控制在合理范围内,从而避免其产生过度兴奋等作用,是目前中医药研究中较为常见的机制探究角度。查阅近10年有关自拟复方、经典方与针刺疗法调控DA系统干预儿童抽动障碍效应机制实验研究的文献资料,对于今后中医药治疗本病的深层次效应机制研究发展不仅具有十分重要的意义,而且也为该领域的临床实践提供更多的基础科学研究依据。Research on the mechanism of Chinese herbal medicine and acupuncture therapy in intervening in childhood tic disorders has made progress.A common angle of exploration in current traditional Chinese medicine(TCM)research is how to effectively regulate the dopamine(DA)system to maintain the effective concentration of DA within a reasonable range,thereby avoiding excessive excitation and other adverse effects.This paper reviews the experimental research literature published in the past decade on the mechanisms of self-designed compound prescriptions,classical prescriptions,and acupuncture therapy in regulating the DA system for intervention in childhood tic disorders.This review not only holds great significance for future research on the deep-level mechanisms of TCM treatment for this disease but also provides more fundamental scientific research evidence for clinical practice in this field.

关 键 词：抽动障碍 儿童 中草药 针刺疗法 多巴胺系统 综述 

分 类 号：R749.94[医药卫生—神经病学与精神病学]