头颈部肿瘤放射治疗患者种植修复策略研究进展  

Research advances on implantation strategy for patients with head and neck cancer radiotherapy

作　　者：戴雨薇 李洁[2] 杨昊楠 吴轶群[2] 孟箭[3] DDAAI Yuwei;LI Jie;YANG Hao-nan;WU Yi-qun;MENG Jian(School of Stomatology,Shandong Second Medical University,Weifang 261053,China;不详)

机构地区：[1]山东第二医科大学口腔医学院,山东潍坊261053 [2]上海交通大学医学院附属第九人民医院口腔第二门诊部,上海交通大学口腔医学院,国家口腔医学中心,国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室,上海市口腔医学研究所,上海201999 [3]徐州市中心医院口腔科,江苏徐州221000

出　　处：《中国实用口腔科杂志》2024年第6期739-743,共5页Chinese Journal of Practical Stomatology

基　　金：国家口腔疾病临床医学研究中心开放课题(NCRCO-202101)。

摘　　要：头颈部恶性肿瘤在口腔临床中较为常见,常需行手术、放射治疗(以下简称“放疗”)和(或)化学治疗等方式联合治疗,患者术后大多存在牙列缺损或面部畸形等问题。口腔种植修复是恢复牙列缺损、咬合功能的主要方法之一。然而,放疗可能会影响种植体早期骨结合及长期稳定性,使头颈部肿瘤放疗患者种植修复策略的合理制定极具挑战。文章先就放疗对种植手术效果的影响做一分析,而后探讨种植体植入时机、放疗与种植体植入和负载时间间隔、放疗剂量、肿瘤部位、种植体植入位置及高压氧辅助治疗对头颈部肿瘤放疗患者种植修复效果的影响,为临床医生提供参考。Head and neck cancer is common in oral clinical practice,which often requires combined treatment such as surgery,radiotherapy and/or chemotherapy.Most patients have dentition defects or facial deformities after surgery.Oral implant restoration is one of the main methods to restore dentition defects and occlusal function.However,radiotherapy may affect the early osseointegration and long-term stability of implants,making it challenging to develop a reasonable strategy for implant restoration in patients with head and neck cancer undergoing radiotherapy.This article analyzes the impact of radiotherapy on implant surgery,and discusses the effect of its timing,the time interval between radiotherapy and implant placement and loading,radiotherapy dose,tumor location,implant placement position,and hyperbaric oxygen therapy on the implant restoration results of head and neck cancer patients,so as to provide reference for clinicians.

关 键 词：口腔种植 头颈部肿瘤 种植体存留率 放射治疗 

分 类 号：R78[医药卫生—口腔医学]