膳食硝酸盐的心血管系统保护机制研究进展  

Research Progress on the Cardiovascular Protection Mechanism of Dietary Nitrate

作　　者：钱林 陈丽蓉 赵佳敏 刘永铭[2,3] QIAN Lin;CHEN Lirong;ZHAO Jiamin;LIU Yongming(The First School of Clinical Medicine,Lanzhou University,Lanzhou 730030,China;Department of Geriatric Cardiovascular Medicine,the First Hospital of Lanzhou University,Lanzhou 730030,China;Gansu Clinical Medical Research Center for Geriatric Diseases,Lanzhou 730030,China)

机构地区：[1]兰州大学第一临床医学院,甘肃省兰州市730030 [2]兰州大学第一医院老年心血管科,甘肃省兰州市730030 [3]甘肃省老年疾病临床医学研究中心,甘肃省兰州市730030

出　　处：《实用心脑肺血管病杂志》2025年第1期117-120,共4页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：甘肃省科技计划项目(20YF8FA079)。

摘　　要：流行病学研究证明,增加蔬菜摄入量可以降低心血管疾病的风险。近年来,主要来源于膳食的硝酸盐对心血管系统的保护作用引起了广泛关注。本文通过回顾相关文献,综述了膳食硝酸盐的心血管系统保护机制,包括降低血压、改善内皮功能、抑制血小板聚集、减轻心肌缺血再灌注损伤(IRI)、降低肺动脉压,提出膳食硝酸盐可用于心血管疾病患者的膳食治疗。Epidemiological studies have shown that increasing vegetable intake can reduce the risk of cardiovascular disease.In recent years,the protective effects of nitrate mainly derived from diet on the cardiovascular system have attracted widespread attention.This article reviews relevant literature and summarizes the cardiovascular protection mechanisms of dietary nitrate,including lowering blood pressure,improving endothelial function,inhibiting platelet aggregation,reducing myocardial ischemia-reperfusion injury(IRI),and lowering pulmonary artery pressure.It proposes that dietary nitrate can be used for dietary treatment of cardiovascular disease patients.

关 键 词：心血管疾病 硝酸盐类 膳食 综述 

分 类 号：R54[医药卫生—心血管疾病]