国家组织药品集中带量采购对某院他汀类药物使用情况的影响  

Effects of state⁃organized centralized procurement of drugs on statin use at a single hospital

作　　者：左慧芳 ZUO Huifang(Xinzheng Public People’s Hospital,Xinzheng 451100,Henan,China)

机构地区：[1]新郑市公立人民医院,河南新郑451100

出　　处：《中国校医》2024年第9期708-711,共4页Chinese Journal of School Doctor

摘　　要：目的探究国家组织药品集中带量采购对某院他汀类药物使用情况的影响。方法所有数据均来源于我院信息系统及相关统计资料,分别对国家组织药品集中带量采购实施前(2018年7月—2019年1月)及国家组织药品集中带量采购实施后(2019年3—9月)我院的用药数据展开分析。对比国家组织药品集中带量采购实施前后他汀类药物使用量、他汀类药物销售金额、他汀类药物的用药频度(DDDs)及限定日费用(DDC)的排序。结果实施国家组织药品集中带量采购后半年内瑞舒伐他汀与普伐他汀同比增长率最高,分别为926.74%、103.81%;其次为氟伐他汀、阿托伐他汀、氨氯地平阿托伐他汀,分别为19.94%、9.90%、8.58%;而辛伐他汀与匹伐他汀同比均出现不同程度的下降,分别为-3.66%、-51.36%。实施国家组织药品集中带量采购后他汀类药物销售金额同比下降14.98%,其中瑞舒伐他汀销售金额同比增长最快,为1030.12%;其次为普伐他汀、氟伐他汀、氨氯地平阿托伐他汀,分别为100.12%、20.79%、3.40%;而匹伐他汀、辛伐他汀、阿托伐他汀销售金额同比呈下降趋势,分别为-93.82%、-91.09%、-55.99%。实施国家组织药品集中带量采购后他汀类药物DDDs明显增加,其中普伐他汀及瑞舒伐他汀DDDs剧增,而匹伐他汀DDDs明显减少。实施国家组织药品集中带量采购后他汀类药物DDC排序出现明显的改变,由氨氯地平阿托伐他汀、阿托伐他汀、瑞舒伐他汀变为瑞舒伐他汀、氨氯地平阿托伐他汀、普伐他汀,其中阿托伐他汀与匹伐他汀排序出现明显下降,DDC下降幅度最大的为辛伐他汀。结论国家组织药品集中带量采购模式下能够有效降低他汀类药物的日均使用费用,减轻患者的用药负担,同时可对调整药品价格提供有效参考。Objective This study was aimed at exploring the effects of centralized,state⁃organized drug procure⁃ment on the use of statins at a single hospital.Methods All data,including related statistical data,were collected from the hospital information system.Data on drug use were analyzed before(July 2018 to January 2019)and after(March 2019 to September 2019)the implementation of state⁃organized centralized drug procurement.Statin consumption,statin sales,fre⁃quency of medication(DDDs)and limited daily cost(DDC)were compared before and after the implementation of centralized drug procurement.Results The growth rates of rosuvastatin and pravastatin were 926.74%and 103.81%respectively,and were followed by those of fluvastatin,atorvastatin and amlodipine atorvastatin,at 19.94%,9.90%and 8.58%,respectively.Simvastatin and pivastatin decreased to different degrees,and had change rates of-3.66%and-51.36%,respectively.After implementation of centralized procurement of drugs organized by the state,the total consumption of statins decreased by 14.98%year on year.The total consumption of rosuvastatin showed the fastest increase(1030.12%)and was followed by pravastatin,fluvastatin,amlodipine and atorvastatin,at 100.12%,20.79%and 3.40%,respectively.The total consumption of pivastatin,simvastatin and atorvastatin decreased year on year,with change rates of-93.82%,-91.09%and-55.99%,respectively.The DDDs of statins significantly increased after the implementation of centralized procurement of drugs,among which the pravastatin and rosuvastatin DDDs increased sharply,whereas the pivastatin DDDs significantly decreased.The DDC ranking of statins changed from amlodipine atorvastatin,atorvastatin and rosuvastatin before,to rosuvastatin,amlodip⁃ine atorvastatin and pravastatin after the nationally orga⁃nized implementation of centralized procurement of drugs.Among them,the rankings of atorvastatin and pivastatin de⁃creased significantly,and simvastatin showed the largest decrease in DDC.Conclusion The national organization of

关 键 词：集中带量采购 他汀类调脂药 限定日费用 用药频度 

分 类 号：R012[医药卫生]